California Office of Environmental Health Hazard Assessment (OEHHA)
United States — California · Binding — Proposition 65 warning law (listings + MADL/NSRL) · Established 1991 · Authored by Karen Pendergrass, Institute for Contaminant Standards · oehha.ca.gov
Quick read
California’s Office of Environmental Health Hazard Assessment runs the science behind Proposition 65, which requires a warning before exposing Californians to listed chemicals — including lead, cadmium, and inorganic arsenic. For some it sets a Maximum Allowable Dose Level (MADL, for reproductive toxicants) or No Significant Risk Level (NSRL, for carcinogens); exposures below these are exempt from the warning requirement. Prop 65 is enforceable law, but it works through warnings and exposure thresholds, not food concentration limits.
Mandate & scope
OEHHA administers the scientific side of California’s Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65). It maintains the list of chemicals known to the state to cause cancer or reproductive harm — lead, cadmium, inorganic arsenic, nickel, and hexavalent chromium compounds are all listed — and derives the exposure levels below which a business is exempt from the warning requirement: No Significant Risk Levels for carcinogens and Maximum Allowable Dose Levels for reproductive toxicants (lead’s MADL of 0.5 µg/day is among the most stringent heavy-metal exposure thresholds anywhere; cadmium’s oral MADL is 4.1 µg/day). Prop 65 is enforced through litigation, including by private plaintiffs, which makes it commercially consequential out of proportion to California’s size. It governs exposure and warnings rather than setting a maximum concentration a food may contain.
Positions across metals
| Metal | Type | Value | Instrument | Effective | Status |
|---|---|---|---|---|---|
| Lead | Prop 65 | multiple — see instrument | Lead and Lead Compounds Listing | — | in-force |
| Cadmium | Prop 65 | 4.1 µg/day oral | Cadmium Listing and Maximum Allowable Daily Level | 1997 | in-force |
| Inorganic arsenic | Prop 65 | value pending | Inorganic Arsenic Compounds Listing | — | in-force |
| Hexavalent chromium | Prop 65 | 8.2 µg/day oral MADL | Hexavalent Chromium Listing and Safe-Harbor Levels | 2008 | in-force |
Where it diverges
Prop 65 MADLs and NSRLs are daily-exposure thresholds (µg/day) — a different basis again from intake-per-body-weight guidance and from food concentration limits — so they are not directly comparable with EFSA, JECFA, EU, or FDA values. Their significance is legal rather than a matter of toxicological consensus: lead’s 0.5 µg/day MADL sits far below the intake implied by most other bodies’ values and drives the warning labels and settlements that shape product reformulation across the US market. The question Prop 65 asks is not “is this number lower than EFSA’s” but “does exposure exceed the level that triggers a mandatory warning.”
Lead
Cadmium
| Body | Type | Value | Instrument |
|---|---|---|---|
| OEHHA | Prop 65 | 4.1 µg/day oral | Cadmium Listing and Maximum Allowable Daily Level |
| JECFA | PTMI | 25 µg/kg bw/month | Provisional Tolerable Monthly Intake for Cadmium |
| Codex | Maximum level | see instrument | Maximum Levels for Cadmium in Food |
| EFSA | TWI | 2.5 µg/kg bw/week | Tolerable Weekly Intake for Cadmium |
| EC | Maximum level | see instrument | Commission Regulation |
| EC | Maximum level | multiple — see instrument | Cadmium maximum levels for cereals |
| EC | Maximum level | see instrument | Commission Regulation |
| EC | Maximum level | multiple — see instrument | Commission Regulation |
| EC | Maximum level | see instrument | EU Regulation 2023 915 maximum levels for contamin… |
| US EPA | Oral RfD | 1 µg/kg bw/day food | EPA IRIS — Cadmium Oral Reference Doses |
| ATSDR | MRL | 0.1 µg/kg bw/day | Minimal Risk Levels for Cadmium |
Inorganic arsenic
| Body | Type | Value | Instrument |
|---|---|---|---|
| OEHHA | Prop 65 | value pending | Inorganic Arsenic Compounds Listing |
| JECFA | BMDL | see instrument | JECFA inorganic arsenic BMDL₀.₅ |
| EFSA | BMDL (no threshold) | no numeric threshold (BMDL basis) | Arsenic in Food |
| EC | Maximum level | see instrument | Commission Regulation |
| EC | — | multiple — see instrument | eu-2015-1006-iAs-rice |
| EC | Maximum level | see instrument | EU Regulation 2023 915 maximum levels for contamin… |
| FDA | Action level | 100 ppb | FDA Closer to Zero — 100 ppb Inorganic Arsenic Act… |
| US EPA | MCL (water) | 10 ppb | Maximum Contaminant Level for Arsenic in Drinking… |
| US EPA | — | value pending | EPA IRIS — Inorganic Arsenic Toxicological Review |
Hexavalent chromium
No other tracked body sets a position for hexavalent chromium; OEHHA is the only one in the index.
Update log
| Date | Event | Instrument | Status |
|---|---|---|---|
| 1997-05-01 | Issued / in force | Cadmium Listing and Maximum Allowable Daily Level | in-force |
| 2008-12-19 | Issued / in force | Hexavalent Chromium Listing and Safe-Harbor Levels | in-force |
Key documents
References
Positions, the update log, and key documents above are generated from the per-instrument regulation pages this body issues, via tools/build-regulator-pages.mjs. The wiki reports what OEHHA has published; it does not endorse it. See HMTc separation policy for why reporting regulatory values is kept architecturally separate from certification threshold-setting.