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Heavy Metal Index

EPA IRIS — Inorganic Arsenic Toxicological Review (January 2025)

The January 2025 EPA IRIS Toxicological Review of Inorganic Arsenic (EPA/635/R-25/005Fa, CASRN 7440-38-2) is the finalized US Environmental Protection Agency reassessment of inorganic arsenic toxicity (EPA IRIS iAs 2025).

Overview

The January 2025 EPA IRIS Toxicological Review of Inorganic Arsenic (EPA/635/R-25/005Fa, CASRN 7440-38-2) is the finalized US Environmental Protection Agency reassessment of inorganic arsenic toxicity (EPA IRIS iAs 2025). It supersedes prior IRIS arsenic values that had been operative for decades, and represents the US federal scientific anchor for inorganic arsenic dose-response that downstream EPA, FDA, and state regulatory actions reference (EPA IRIS iAs 2025).

The full quantitative outputs (oral RfD, inhalation RfC, oral cancer slope factor, inhalation unit risk, critical study identification per endpoint) require detailed extraction from the approximately 100+ page review document and are pending consolidation (EPA IRIS iAs 2025). Once those values are extracted from the full text, this regulation page will record them with the verbatim agency-stated values.

Sources

  • EPA IRIS iAs 2025 — EPA, January 2025. IRIS Toxicological Review of Inorganic Arsenic (EPA/635/R-25/005Fa).

References

Works cited in this page’s text, in first-appearance order. See Sources for this page’s source inventory. Each title links to its source record, which carries the ingest receipt, the extracted values, and the file hash of the document it was built from.

  1. IRIS Toxicological Review of Inorganic ArsenicU.S. Environmental Protection Agency, Center for Public Health and Environmental Assessment · EPA/635/R-25/005Fa, U.S. Environmental Protection Agency, Integrated Risk Information System · 2025 · iris.epa.govGovernment

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