Xiong and colleagues followed mother-infant pairs at Peking University People’s Hospital and related trace elements in maternal hair to the infant gut microbiome, metabolome, and resistome through the first year.
Key numbers
The WikiBiome corpus note states 146 mother-infant pairs. Stool was collected at 3, 6, and 12 months (amplicon sequencing n = 353, metagenomics n = 65, metabolomics n = 198). Maternal hair trace elements were measured in 119 mothers. Shannon diversity of the infant gut microbiome at 3 months correlated positively with selenium and negatively with copper. Bifidobacterium relative abundance in the infant gut microbiome increased under high exposure to aluminum and manganese. The note states that high copper and arsenic exposure may induce enrichment of antibiotic resistance genes in the infant gut. It names 56 differential metabolites between the first and second visits and 515 between the second and third.
Evidence fitness
The record supports a birth-cohort association between maternal hair trace elements and the infant gut microbiome. It does not support a concentration of those elements in any food, and it does not state a limit.
Limitations
This page records the WikiBiome corpus note. It is not a new extraction from a local copy of the paper. Hair is not a food sample. The note does not print the hair concentrations.
Related evidence
Update history
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