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Heavy Metal Index

Determination of Element Concentrations in Commercial Infant Formulas Using Atomic Absorption Spectrometry

Source

This study measured heavy metals, essential elements, and minerals in 20 commercial infant formula samples collected from pharmacies and supermarkets in Malatya, Turkey.

Page snapshot
Cited by9 pages
Metals measured5
Evidence tierA
Year2017

Overview

This study measured heavy metals, essential elements, and minerals in 20 commercial infant formula samples collected from pharmacies and supermarkets in Malatya, Turkey. The HMT&C-relevant values are Al and Pb in powdered formula, with Fe, Zn, Mg, Ca, K, and Na reported for nutritional context.

Key numbers

Age-group mean concentrations in infant formula (Table III; mean +/- SD):

Element0-6 months (n=10)7-12 months (n=10)
Al1.29 +/- 0.66 ug/g1.54 +/- 0.35 ug/g
Pb0.16 +/- 0.02 ug/g0.18 +/- 0.08 ug/g
Fe61.34 +/- 13.72 ug/g72.6 +/- 4.05 ug/g
Zn29.72 +/- 4.04 ug/g34.64 +/- 6.32 ug/g
Mg0.51 +/- 0.08 mg/g0.50 +/- 0.15 mg/g
Ca4.19 +/- 0.45 mg/g4.35 +/- 0.96 mg/g
K6.53 +/- 1.09 mg/g6.08 +/- 2.27 mg/g
Na0.95 +/- 0.19 mg/g1.89 +/- 0.75 mg/g

Source-reported method performance and exposure framing:

  • LOD/LOQ were 1.90/6.35 ug/g for Al, 0.01/0.02 ug/g for Pb, 0.33/1.12 ug/g for Fe, 0.16/0.53 ug/g for Zn, and 0.07/0.24 ug/g for Mg.
  • The paper states that none of the samples contained Al or Pb in amounts representing a health hazard for infants.
  • Calculated daily intake for 0-6 month infants was 19.4 ug/kg bw/day Al and 2.4 ug/kg bw/day Pb.
  • Calculated daily intake for 7-12 month infants was 23.1 ug/kg bw/day Al and 2.7 ug/kg bw/day Pb.

Methods (brief)

Twenty infant formula samples from five manufacturers were collected from pharmacies and supermarkets in Malatya, Turkey. Samples were dried at 105 C for 24 hours. About 0.50 g sample or NIST-SRM 8418 Wheat Gluten was microwave digested in Teflon vessels with 7 mL concentrated nitric acid and 1 mL hydrogen peroxide, then diluted to 25 mL. Al, Ca, Fe, K, Mg, Na, and Zn were measured by flame AAS and Pb by graphite furnace AAS using a PerkinElmer AAnalyst 800 system. Microwave digestion used a Milestone Start D closed-vessel system. Recoveries against NIST-SRM 8418 were 92% for Al, 87% for Ca, 93% for Fe, 89% for K, 97% for Mg, 96% for Na, 90% for Pb, and 91% for Zn.

Implications

Standards work: This is direct powdered infant formula occurrence evidence for Al and Pb in a Turkish retail sample set, split by age-labeled formula group.

Courses: Useful for showing how the same formula survey can support toxic-element screening and nutrient/mineral context without combining the two endpoints.

App: Provides powder-basis occurrence fields for Al and Pb in commercial infant formula, with Fe, Zn, Mg, Ca, K, and Na as nutritional context only.

Microbiome: Not addressed.

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Verification notes

  • Fresh auto-fetch ingest 2026-05-19 from the gap-driven infant-formula wishlist.
  • Strict brand firewall: this page reports manufacturer count and formula age groups, but does not name or rank commercial brands.
  • The paper reports total Pb and Al only; no arsenic, mercury, or chromium speciation issue applies.
  • Methods vendor/equipment/reference-material names are retained under Part 12 Exception 2.

Update history

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