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Heavy Metal Index

Heavy metals induced health risk assessment through consumption of selected commercially available spices in Noakhali district of Bangladesh

Overview

This is the peer-reviewed Heliyon publication of the work indexed in the HMI library as a medRxiv preprint (islam2023-noakhali-spices-bangladesh). Islam et al. measured lead, cadmium, chromium, copper, and iron in 19 spice samples from Noakhali District, Bangladesh, using AAS. The study includes two cumin samples: one non-branded (S-14, Jirar Gura, Cuminum cyminum) and one branded (S-16, Jirar Gura, Cuminum cyminum). The paper’s main health risk findings focused on chromium (Cr THQ values >1 for several spices including chili powder and turmeric) rather than lead (Pb) or cadmium (Cd), which remained below individual THQ=1. Cardamom had the highest Pb (15.47 mg/kg) of all spices; cumin was not among the high-risk spices for any metal in this dataset.

Key numbers

Spice-level heavy metal concentrations from paper text and figures (mg/kg, dry weight, AAS, LOD 0.01 ppm/mL):

  • Cardamom (S-7): highest Pb 15.47 +/- 1.93 mg/kg
  • Cinnamon (S-12): Pb 10.05 +/- 1.22 mg/kg
  • Coriander leaf (S-17): highest Cd 1.65 +/- 0.011 mg/kg
  • Bay leaf (S-18): highest Cr 31.99 +/- 3.97 mg/kg
  • Dried chili (S-6): highest Cu 18.84 +/- 1.97 mg/kg
  • Black pepper (S-19): highest Fe 9.29 +/- 1.71 mg/kg

Cumin-specific data (from preprint Table 2 EDI values, S-14 and S-16; published version may differ slightly):

SampleIR (kg/day/person)EDI PbEDI CdEDI CrEDI CuEDI Fe
S-14 (non-branded cumin)0.000570.000010.000010.000130.000040.00019
S-16 (branded cumin)0.000410.000000.000010.000150.000120.00027

THQ values for cumin S-14: Pb 0.00283, Cd 0.01227, Cr 0.43371, Cu 0.00101, Fe 0.02696; TTHQ 0.47678 (all <1). THQ values for cumin S-16: Pb 0.00135, Cd 0.01063, Cr 0.50666, Cu 0.00292, Fe 0.03918; TTHQ 0.56073 (all <1). All cumin TTHQ values <1, indicating acceptable health risk at Noakhali consumption rates.

Copper in branded cumin (S-16): 13.81 +/- 2.38 mg/kg was noted in text as third highest Cu across all spices studied.

Concentration data for cumin seeds (inferred from EDI back-calculation at stated IR 0.00057 kg/day, body weight 60 kg):

  • Non-branded cumin (S-14) Pb: very low (EDI 0.00001); approximate concentration ~0.26 mg/kg
  • Note: concentration values were not tabulated per spice in the preprint; published version Table 1 likely contains them

Methods (brief)

AAS: PerkinElmer PinAAcle 900H with dual beam optics continuum source double-beam background correction using high-intensity deuterium arc lamp. Wet digestion: 1:4 HNO3/H2SO4 mixture at 130 degrees C for 1 hour, then 2 mL H2O2 added, re-heated. Filtered and transferred to 50 mL volumetric flask. LOD 0.01 ppm/mL. Linearity R2 ranges 0.9897-0.9983.

Near-duplicate note

This paper is the peer-reviewed Heliyon publication of the preprint at doi:10.1101/2023.02.06.23285555 (cite_key: islam2023-noakhali-spices-bangladesh). Both pages are retained; the published version has undergone peer review and may contain corrected or updated concentration tables. The cumin.md page should cite the published version where both are available.

Update history

No substantive edit history is available in this build. The full commit record is available in git.