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Heavy Metal Index

Prenatal exposure to trace elements impacts mother-infant gut microbiome, metabolome and resistome during the first year of life

Xiong and colleagues recruited 146 mother-infant pairs. The abstract states that stool was collected at 3, 6, and 12 months after delivery for amplicon sequencing (N = 353), metagenomics (N = 65), and metabolomics (N = 198). Trace elements were measured in maternal hair (N = 119).

The abstract states that those trace elements affect diversity and composition of the infant gut microbiome. Shannon diversity in 3-month-old infants correlated positively with selenium and negatively with copper. Relative abundance of Bifidobacterium increased under high exposure to aluminum and manganese. High levels of copper and arsenic exposure may induce enrichment of antibiotic resistance genes in the infant gut. The abstract also states that infants and their mothers had distinct microbial diversity and composition during the first year, and that the bacterial community structures gradually approached one another.

This page records that bibliographic identity and those abstract statements. It does not set a food concentration or a certification limit.

Evidence fitness

Supports cohort findings that prenatal hair trace elements, including aluminum and arsenic, track with infant gut microbiome and resistome measures. Does not support a concentration of those elements in any food.

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