Can Liu and colleagues exposed adult zebrafish for 14 days to antimony at 0, 30, 300, and 3000 µg/L. The 30 µg/L group is described as chosen because it matches a chronic aquatic limit. The paper reports physiological, intestinal microbiota, and metabolomic responses. The intestine carried a greater antimony burden than other tissues in the narrative. Tissue concentrations are not printed as a table that this page can quote, so none are given. This is an exposure experiment, not a food survey.
Key numbers
Nominal water concentrations were 0, 30, 300, and 3000 µg/L antimony for 14 days. Figure summaries are mean ± standard deviation with n = 3. Measured antimony in the solutions showed an average deviation of less than 20% from those nominal values, and the nominal concentrations were used afterward. A separate acute test in adult zebrafish, by nonlinear regression, gave LC50 values of 79.67 mg/L at 24 h, 70.53 mg/L at 48 h, 60.63 mg/L at 72 h, and 56.71 mg/L at 96 h. Those LC50 figures are in mg/L. They are a different experiment from the 14-day µg/L doses. No food or drinking-water occurrence value is reported.
Methods (brief)
Subacute waterborne exposure of Danio rerio. China, Hunan University of Humanities, Science and Technology.
Evidence fitness
The nominal doses and the acute LC50 series support a description of the exposure design. They do not support a food concentration.
Limitations
Tissue concentrations are not transcribed. The chronic-limit sentence is the authors’ rationale for 30 µg/L, not a new regulatory instrument. The LC50 series is printed as Sb, without a species split in that sentence.
Related evidence
Update history
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