Seafood Toxicant Exposure During Pregnancy, Lactation, and

Overview

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Key numbers

The worker extracted the full PDF text with layout preservation twice and compared extraction hashes before commit. The following lines are copied from numeric/table-bearing regions of the PDF and retain the source units and wording where legible:

• evaluate whether an association exists. Therefore, the objectives strategy for this ScR (Supplemental Table 1). Medical Subject
• exposure and outcome pairs have sufficient evidence for date range was January 2000 to July 2023.
• Protocol development reviewer. Supplemental Table 2 shows reasons for excluding full-
• review (Table 1) (15). The prioritized toxicants were assessed in design, cohort name (if applicable), country, and sample size.
• child age, percent female, and anthropometrics. For the purpose studies, from 20% to 86% female, and age range varied from
• of this study, child exposure biomarkers assessed through cord birth to 17 y. Participant characteristics are provided in Table 2.
• Table 2). (28,87), and magnesium (Mg; n ¼ 1) (87); no study evaluated
• 101. and As (62,71,87) and child exposure biomarkers. The dren is shown in Table 4.
• Ballester et al., PCS, INMA, Spain, N Mean (range): 31.0 Mean (SD): Newborn; 47.6% NR Spain: 92.2%; Maternal education: NR
• University: 35.2%
• Barbone et al., PCS, NR, Italy, N ¼ NR NR Mean (SD): 25.1 (3.7) Weight (g): Fine NR NR Mean (SD):
• 2020 (22) 53, Pregnancy mo; 47.2% motor-adaptive area Breastfeeding: 7.9
• Beck et al., 2023 PCS, Odense Child n (%): n (%): 18–36 mo; 46.0% NR NR n (%): Median (IQR):
• Chan et al., 2021 PCS, Hong Kong Birth NR NR Mean (SD): 8.1 (0.9) Mean (SD): BMI (kg/ NR %: NR
• Cunha et al., 2018 PCS, NR, Brazil, N ¼ Mean (SD): Urban: NR 0–59 mo; 50.3% Mean (SD): NR NR Mean (SD):
• TABLE 2 (continued )
• Da Cunha et al., PCS, NR, Brazil, N ¼ Mean (SD): 27.3 (5.0) Mean (SD): 0–90 d; 50.0% Mean (SD): Weight at NR NR Mean (SD): Breastfeed
• Davidson et al., PCS, SCDS, Republic Range: enrollment NR 0–30 mo; 50.7 NR NR NR NR
• Deroma et al., PCS, Friuli Venezia Mean (SD): Age at NR Mean (SD): Age at n (%): NR n (%): Breastfeeding: 89%
• Emeny et al., 2019 PCS, New Hampshire Mean (range): At Mean (range): 0–12 mo; 49.0% Median (range): n (%): n (%): n (%):
• TABLE 2 (continued )
• Fabelova et al., PCS, European Mean (SD): Mean: Newborns; 47.9% NR NR %: NR
• Fruh et al., 2021 PCS, Project Viva, Mean (SD): 32.4 (5.0) NR Mean (SD): NR %: %: NR
• TABLE 2 (continued )
• Geer et al., 2012 PCS, University n (%): NR Newborns; NR NR n (%): n (%): NR
• Gennings et al., PCS, SELMA, Sweden, NR Mean (SD): 0–7 y; At birth: 48.0: 7 Mean (SD): NR %: NR
• 2020 (36) N ¼ 1312, Pregnancy Weight (kg): y: 50.0% Birth weight (g): Maternal higher
• Golding et al., PCS, ALSPAC, United n (%): NR 8 y; NR NR n (%): n (%): —
• TABLE 2 (continued )
• Goudarzi et al., PCS, Hokkaido Study Mean (SD): 29.7 (4.7) Mean (SD): NR; 56.2% Mean (SD): Participants from n (%): NR
• Grandjean et al., PCS, Faroe Islands Mean (SD): 28.0 (5.8) Mean (SD): Newborns; 48.9% Mean (SD): NR NR NR
• Halldorsson et al., PCS, Danish National Median (IQR): Median (IQR): NR; 47.0% Mean (SD): NR %: NR
• Han et al., 2018 PCS, Laizhou Wan Mean (SD): 28.35 Mean (SD): Newborns; 48.8% NR NR n (%): NR
• TABLE 2 (continued )
• 4 y: 33; 20.0% United States: 74 <12 y: 10
• Hu et al., 2016 PCS, Laizhou Wan n (%): n (%): 1 y; 47.8% Mean (SD): NR n (%): NR
• TABLE 2 (continued )
• Jeong et al., 2017 PCS, Mothers and n: NR 60 mo; 46.8% n: NR n: NR
• Julvez et al., 2016 PCS, INMA, Spain, N n: NR 14 mo–5 y; 49.0% NR n: n: n:
• Kim et al., 2016 PCS, CHECK, Korea, N Mean (SD): 33.3 (3.9) Mean (SD): BMI (kg/ Newborns; NR NR NR n (%): NR
• Kim et al., 2018 PCS, Mothers and n (%):6 mo of child: NR 6–36 mo; 48.0% n (%):Birth weight NR n (%):Maternal n (%): Breastfeeding:
• TABLE 2 (continued )

Methods (brief)

• review (Table 1) (15). The prioritized toxicants were assessed in design, cohort name (if applicable), country, and sample size.
• blood samples were considered to be maternal markers. Through
• America (n ¼ 3), and Africa (n ¼ 2). Sample sizes ranged from 17 (22–24,28,29,33,36–39,53,44,47–51,56,57,60,67–70,79–81,
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)
• sample size, exposure education)

Implications

This page makes the source discoverable for category-level evidence routing. Values remain source-native and should be used only with the stated matrix, species, basis, geography, and censoring context from the paper. The page does not convert total mercury to methylmercury or use total arsenic as inorganic arsenic.

Wiki pages this source may touch

• Infant Formula Powder
• Fish — marine, predatory (tuna, swordfish, shark, king mackerel)
• Fish — marine, non-predatory (sardines, anchovies, salmon, cod)
• Mercury
• Mercury
• Cadmium
• Lead
• Arsenic

Verification notes

• Identity check: DOI, raw handle, candidate cite-key, and SHA-256 were compared against existing wiki/sources/ pages before creation.
• Full-PDF read: pdftotext -layout was run on the full PDF twice; extracted text hashes matched before the page was written.
• Numeric verification: numeric/table-bearing lines were selected mechanically from the verified extraction and preserved without unit conversion or rounding.
• Brand firewall: the worker skips PDFs when extracted numeric lines appear brand/manufacturer-sensitive; this page contains category-level or species-level evidence only.
• HMTc firewall: no threshold, percentile, pass/fail, clean/dirty, or certification math is stated.

Update history

The five most recent substantive edits to this page, classified major (evidence or structure moved), correction (a published value or statement was wrong and has been fixed), or minor (narrative rewritten without changing the underlying evidence). Each description is derived from what the edit did to this page; the linked commit is the authoritative record, routine regeneration passes are excluded, and the full version history lives in git. When DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.