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Obsessive skincare and liver toxicity: a case report on

This source page is a mechanical bulk-ingest record for a PDF in the research-pulls corpus.

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Overview

This source page is a mechanical bulk-ingest record for a PDF in the research-pulls corpus. It preserves source-level identity, routeable product/analyte scope, and exact extracted numeric lines for later human or fresh-context audit. It does not derive HMTc thresholds, percentiles, or brand-by-brand comparisons.

Key numbers

The worker extracted the full PDF text with layout preservation twice and compared extraction hashes before commit. The following lines are copied from numeric/table-bearing regions of the PDF and retain the source units and wording where legible:

  • In dermatological products, TiO2 may be used either as a summarized in Table 1.
  • inorganic ultraviolet (UV) filter, primarily in sunscreens but Table 1. Summary of biochemical analysis of patient by
  • Idiosyncratic, or unpredictable hepatotoxicity, also known ALT 57 U/L 0 - 55
  • high amounts of titanium, 16.60 μg/L (Table 2);
  • Table 2. Heavy Metals Extended Profile. We reviewed the literature for relevant materials
  • Titanium (Ti) 16.60 μg/L 0.00 - 1.00 long-term or repeated exposure studies have been
  • Arsenic (As) 0.66 μg/L 0.00 - 12.00
  • Mercury (Hg) 0.78 μg/L 0.00 - 10.00 that demonstrated a small increase in titanium levels in the
  • Nickel (Ni) 1.01 μg/L <3.3 weeks (21). In our case, while TiO₂ particles are often used
  • Cadmium (Cd) 0.50 μg/L <5.0 possible to determine the exact form due to the patient’s
  • Aluminum (Al) 1.12 μg/L 1.0 - 14.0 use of multiple skincare products. Nonetheless, previous
  • laboratory findings summarized in Table 1 provide a clear oxygen species (ROS) and other oxidative products, as well
  • is often associated with metabolic derangements and high amounts of TiO2 were found in her blood, which could

Methods (brief)

  • Analytical method details were not mechanically resolved from extracted text.

Implications

This page makes the source discoverable for category-level evidence routing. Values remain source-native and should be used only with the stated matrix, species, basis, geography, and censoring context from the paper. The page does not convert total mercury to methylmercury or use total arsenic as inorganic arsenic.

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Verification notes

  • Identity check: DOI, raw handle, candidate cite-key, and SHA-256 were compared against existing the linked reference record pages before creation.
  • Full-PDF read: pdftotext -layout was run on the full PDF twice; extracted text hashes matched before the page was written.
  • Numeric verification: numeric/table-bearing lines were selected mechanically from the verified extraction and preserved without unit conversion or rounding.
  • Brand firewall: the worker skips PDFs when extracted numeric lines appear brand/manufacturer-sensitive; this page contains category-level or species-level evidence only.
  • HMTc firewall: no threshold, percentile, pass/fail, clean/dirty, or certification math is stated.

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