Overview
This source page is a mechanical bulk-ingest record for a PDF in the research-pulls corpus. It preserves source-level identity, routeable product/analyte scope, and exact extracted numeric lines for later human or fresh-context audit. It does not derive HMTc thresholds, percentiles, or brand-by-brand comparisons.
Key numbers
The worker extracted the full PDF text with layout preservation twice and compared extraction hashes before commit. The following lines are copied from numeric/table-bearing regions of the PDF and retain the source units and wording where legible:
- modifications may occur, making the alterations heritable (see (3)).
- concentration of MeHg in the cord blood is below 10 nM (~2.2 µg/L) and reaches 100 nM
- (~21.5 µg/L) if the diet is based primarily on seafood (see (26,27)). A safety maximum limit
- for cord blood was defined at 5.8 µg/L (~27 nM) (28). Therefore, there is genuine concern
- aged children (mean PFOS concentration in maternal serum 12.8 ng/mL) (37). Another
- The main findings of the studies reviewed here are summarized in Table 1 (MeHg) and
- MeHg or PFOS/PFOA to elicit similar effects as in the 2D culture of NSCs (see Table 1).
- embryos (E14.5) undergo cell cycle arrest following 48 h exposure to MeHg at ranges from
- neous differentiation. Rat NSCs exposed to MeHg at ranges from 2.5 nM to 10 nM for 48 h
- Human cells exposed to a range of concentrations from 1 to 50 nM of MeHg show de-
- MeHg (0.1 or 1 mg/kg/day i.p. GD11-21) (75). However, no change in the proliferation or
- or PFOA (11.3 and 8.7 mg/kg bodyweight, respectively) at postnatal day 10 increased the
- 30 min, without reducing cell viability. In addition, the mean burst rate (MBR) was
- (1 µM) for 30 min significantly decreased mean spike rate (MSR) and mean network bursts
- Table 1. Studies reporting the effects of MeHg exposure in NSCs.
- Table 2. Studies reporting on the effects of PFOS or PFOA in NSCs.
- measured in NSCs exposed to 2.5 and 5 nM were 0.4 and 0.7 ppm respectively, which are
- MeHg from the maternal diet (up to 0.3 ppm; (87)). The upregulation of p16 and p21 that
- dynamic process. We showed earlier that in utero exposure to 0.5 mg/kg/day MeHg from
- concentration found in the mouse brain was about 0.9 ppm (93), in the same order of mag-
-
- Johnson, S.C.; Pan, A.; Li, L.; Sedensky, M.; Morgan, P. Neurotoxicity of Anesthetics: Mechanisms and Meaning from Mouse
Methods (brief)
- exposure (100–400µM) in various human cell lines and blood samples (94–96). These stud-
-
- Skogheim, T.S.; Weyde, K.V.F.; Aase, H.; Engel, S.M.; Surén, P.; Øie, M.G.; Biele, G.; Reichborn-Kjennerud, T.; Brantsæter,
Implications
This page makes the source discoverable for category-level evidence routing. Values remain source-native and should be used only with the stated matrix, species, basis, geography, and censoring context from the paper. The page does not convert total mercury to methylmercury or use total arsenic as inorganic arsenic.
Wiki pages this source may touch
- Fish — marine, non-predatory (sardines, anchovies, salmon, cod)
- Seaweed/kelp foods (nori, wakame, kombu, dulse — as food products)
- Mercury
- Mercury
- Arsenic
- Chromium
Verification notes
- Identity check: DOI, raw handle, candidate cite-key, and SHA-256 were compared against existing
wiki/sources/pages before creation. - Full-PDF read:
pdftotext -layoutwas run on the full PDF twice; extracted text hashes matched before the page was written. - Numeric verification: numeric/table-bearing lines were selected mechanically from the verified extraction and preserved without unit conversion or rounding.
- Brand firewall: the worker skips PDFs when extracted numeric lines appear brand/manufacturer-sensitive; this page contains category-level or species-level evidence only.
- HMTc firewall: no threshold, percentile, pass/fail, clean/dirty, or certification math is stated.
Update history
The five most recent substantive edits to this page, classified major (evidence or structure moved), correction (a published value or statement was wrong and has been fixed), or minor (narrative rewritten without changing the underlying evidence). Each description is derived from what the edit did to this page; the linked commit is the authoritative record, routine regeneration passes are excluded, and the full version history lives in git. When DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.