Overview
This source page is a mechanical bulk-ingest record for a PDF in the methylmercury infant-formula research pull. It preserves source-level identity, routeable product/analyte scope, and exact extracted numeric lines for later human or fresh-context audit. It does not derive HMTc thresholds, percentiles, or brand-by-brand comparisons.
Key numbers
The worker extracted the full PDF text with layout preservation twice and compared extraction hashes before commit. The following lines are copied from numeric/table-bearing regions of the PDF and retain the source units and wording where legible:
- Nieky van Veggel MSc CBiol FHEA 1*
- ISSN: 2396-9776
- to the PICO. A further 5 records were excluded because they investigated the use of meat-meal with
- carbohydrate biscuit rather than raw meat, 1 record was excluded as it was non-primary research and 1 record
- excluded for investigating non-urinary parameters. The study by Dijcker et al., (2012) identified that currently,
- Population: Dogs aged between 1.3 to 16.1 years of age, 13 female (of
- which 4 entire), 10 male (of which 4 entire), bodyweight range
- Intervention details: Treatment group 1 (n = 23): Fed raw food over a 4-week period
- Treatment group 2 (n = 23): complete and balanced dry
- ISSN:2396-9776
- next review date: 20 Jan 2018 total pages: 7
- Study design: Cohort (study 1) and RCT (study 2) in crossover design
- A single urine sample was collected in week 4 of the diet by the
- containing 2N HCl. Samples were stored at -20 °C until
- (relevant to PICO question): Uca concentration was higher in dogs fed dry diet (TG2)
- Small sample size (n = 23)
- promoting substances such as calcium and uric acid (Robertson et al., 1979). This concern has been steadily
- increasing (Lulich et al., 1999) which has led to the association of a high protein diet with the increased risk of
- renal damage (Singer, 2003). Interest in the health benefits of a protein fed diet is increasing, however studies
- to human health (Joffe and Schlesinger, 2002; Strohmeyer et al., 2006; Finley, et al., 2006; Lefebvre et al.,
- It was noted at the British Small Animal Veterinary Association (BSAVA) 2016 Congress, that standardised
- clients correctly. This lack of evidence-based peer reviewed research was addressed by Goh (2016), who found
- healthier or more nutritionally balanced than other diets (Michel, 2006; van Veggel & Armstrong, 2017).
- ISSN:2396-9776
- next review date: 20 Jan 2018 total pages: 7
- Databases searched and dates CAB Abstracts (1973-2017), PubMed (1950-2017)
- Total relevant papers when duplicates removed 1
- ISSN:2396-9776
- next review date: 20 Jan 2018 total pages: 7
-
- Dijcker, J. C., Hagen-Plantinga, E. A., Everts, H., Bosch, G., Kema, I. P. and Hendriks, W. H. (2012) ‘Dietary
-
- Finley, R., Reid-Smith, R., Ribble, C., Popa, M., Vandermeer, M. and Aramini, J. (2008) ‘The occurrence and
- three Canadian cities.’ Zoonoses and Public Health, 55(8–10) pp. 462–469. DOI:
-
- Finley, R., Reid-Smith, R. and Weese, J. S. (2006) ‘Human health implications of Salmonella-contaminated
- Diseases Society of America, 42(5) pp. 686–691. DOI: http://dx.doi.org/10.1086/500211
-
- Joffe, D. J. and Schlesinger, D. P. (2002) ‘Preliminary assessment of the risk of Salmonella infection in dogs
- fed raw chicken diets.’ The Canadian Veterinary Journal = La Revue Veterinaire Canadienne, 43(6) pp. 441–
-
- Lefebvre, S. L., Reid-Smith, R., Boerlin, P. and Weese, J. S. (2008) ‘Evaluation of the risks of shedding
- Zoonoses and Public Health, 55(8–10) pp. 470–480. DOI: http://dx.doi.org/10.1111/j.1863-
- L.L. and Nakagawa, Y. (1999) ‘Epidemiology of canine calcium oxalate uroliths.’ Veterinary Clinics of North
- America: Small Animal Practice, 29(1) pp. 113-122. DOI: http://dx.doi.org/10.1016/S0195-5616(99)50007-
-
- Lunn, K. F. (2011) ‘Raw Food Diets in Dogs: Concerns for Canine and Human Health.’ Advances in Small
- Animal Medicine and Surgery, 24(2) pp. 1–2. DOI: http://dx.doi.org/10.1016/j.asams.2011.01.001
Methods (brief)
- A single urine sample was collected in week 4 of the diet by the
- owner through natural voiding. Urine sample was divided
- containing 2N HCl. Samples were stored at -20 °C until
- Uox was measuring using isotope dilution mass spectrometry,
- whereas Uca was measured atomic absorption spectroscopy.
- Small sample size (n = 23)
Implications
This page makes the source discoverable for category-level evidence routing. Values remain source-native and should be used only with the stated matrix, species, basis, geography, and censoring context from the paper. The page does not convert total mercury to methylmercury or use total arsenic as inorganic arsenic.
Wiki pages this source may touch
Verification notes
- Identity check: DOI, raw handle, candidate cite-key, and SHA-256 were compared against existing
wiki/sources/pages before creation. - Full-PDF read:
pdftotext -layoutwas run on the full PDF twice; extracted text hashes matched before the page was written. - Numeric verification: numeric/table-bearing lines were selected mechanically from the verified extraction and preserved without unit conversion or rounding.
- Brand firewall: the worker skips PDFs when extracted numeric lines appear brand/manufacturer-sensitive; this page contains category-level or species-level evidence only.
- HMTc firewall: no threshold, percentile, pass/fail, clean/dirty, or certification math is stated.
Update history
The five most recent substantive edits to this page, classified major (evidence or structure moved), correction (a published value or statement was wrong and has been fixed), or minor (narrative rewritten without changing the underlying evidence). Each description is derived from what the edit did to this page; the linked commit is the authoritative record, routine regeneration passes are excluded, and the full version history lives in git. When DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.