Methylmercury and Brain

Overview

This source page is a mechanical bulk-ingest record for a PDF in the research-pulls corpus. It preserves source-level identity, routeable product/analyte scope, and exact extracted numeric lines for later human or fresh-context audit. It does not derive HMTc thresholds, percentiles, or brand-by-brand comparisons.

Key numbers

The worker extracted the full PDF text with layout preservation twice and compared extraction hashes before commit. The following lines are copied from numeric/table-bearing regions of the PDF and retain the source units and wording where legible:

• suggest that the relative imprecision may be as much as 50%, or greater, thereby substantially
• Similarly, more recent studies (as outlined here and in Table 1) have shown mixed results
• delayed neurodevelopment in infants posed by fairly low ranges of MeHg exposure.32
• Table 2. The regression analyses used to evaluate the data from the NYC study indicated no
• general be carried out with a relative imprecision better than 5%. To assess the validity of
• imprecision was 25-30%, and almost twice as much for maternal hair. Thus, the total
• recommended a provisional tolerable weekly intake of 200 μg (or 3.3 μg/kg body weight).
• 50% has been documented for a commonly used exposure biomarker, and such imprecision
• 1978 Exposure limit of 3.3 μg/kg per week based on toxicity in adults; Cree children in Canada assessed at low MeHg exposure
• 2000 National Research Council (U.S.) supports exposure limit of 0.1 μg/kg per day
• 2003 Updated international exposure limit of 1.6 μg/kg per week
• (Lederman et al., 329/738 pregnant women fish/seafood m = 7.8 μg/L Bayley Scales β= —4.2, p<0.001

Methods (brief)

• growth rate of 1 cm per month, a hair sample of 8 cm taken at parturition will mainly reflect
• usually focuses on the laboratory performance as such, and atomic absorption analyses can
• concentrations were measured in two sets of hair samples, one 9-cm sample reflecting the
• the Seychelles was characterized from the mercury content of maternal hair collected six
• mercury concentrations by atomic absorption and the relative wealth of epidemiological

Implications

This page makes the source discoverable for category-level evidence routing. Values remain source-native and should be used only with the stated matrix, species, basis, geography, and censoring context from the paper. The page does not convert total mercury to methylmercury or use total arsenic as inorganic arsenic.

Wiki pages this source may touch

• Fish — marine, predatory (tuna, swordfish, shark, king mackerel)
• Fish — marine, non-predatory (sardines, anchovies, salmon, cod)
• Shellfish (shrimp, crab, lobster, clams, oysters, mussels)
• Mercury
• Mercury

Verification notes

• Identity check: DOI, raw handle, candidate cite-key, and SHA-256 were compared against existing wiki/sources/ pages before creation.
• Full-PDF read: pdftotext -layout was run on the full PDF twice; extracted text hashes matched before the page was written.
• Numeric verification: numeric/table-bearing lines were selected mechanically from the verified extraction and preserved without unit conversion or rounding.
• Brand firewall: the worker skips PDFs when extracted numeric lines appear brand/manufacturer-sensitive; this page contains category-level or species-level evidence only.
• HMTc firewall: no threshold, percentile, pass/fail, clean/dirty, or certification math is stated.

Update history

The five most recent substantive edits to this page, classified major (evidence or structure moved), correction (a published value or statement was wrong and has been fixed), or minor (narrative rewritten without changing the underlying evidence). Each description is derived from what the edit did to this page; the linked commit is the authoritative record, routine regeneration passes are excluded, and the full version history lives in git. When DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.