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Heavy Metal Index
Laboratory electrochemical apparatus illustrating gold nanoflower biosensor research context.

N-Hydroxysuccinimide crosslinked graphene oxide-gold nanoflower modified SPE electrode for sensitive detection of chloramphenicol antibiotic

Overview

Ali and colleagues developed a screen-printed electrode (SPE) modified with graphene oxide cross-linked by N-hydroxysuccinimide and decorated with gold nanoflowers (AuNFs) for the electrochemical detection of chloramphenicol. Gold is the analytical reagent providing electrochemical signal amplification; it is not measured as a food contaminant. Chloramphenicol is an antibiotic banned in food-producing animals in the EU (zero MRL), making sub-ppb detection capability relevant to residue surveillance in animal-derived foods.

Key numbers

LOD: 1 nM chloramphenicol. Linear range: 0.05 to 100 µM. RSD 4.0% (n=3). Sensor validated in spiked poultry feed, milk, honey, egg, blood serum, and powdered milk matrices with recoveries reported.

Implications for the wiki

This paper documents gold nanoparticle/nanoflower platforms as a detection tool for veterinary antibiotic residues in food, relevant to Gold as a section on AuNP analytical applications. No food occurrence data for gold or any heavy metal are provided.

Update history

No substantive edit history is available in this build. The full commit record is available in git.