This materials paper reports a porous bismuth framework built from ellagic acid, made in water from reagents including dietary-supplement-grade ellagic acid, and tests its stability, gas uptake and cytotoxicity in one cell line. In promyelocytic HL-60 cells the material showed low cytotoxicity, with 80 percent inhibition only at 1000 µg/mL.
Key numbers
This paper reports no numerical findings relevant to bismuth exposure.
Methods (brief)
Synthesis under ambient aqueous conditions, structural characterization, colloidal stability testing, in vitro cytotoxicity in HL-60 cells over 24 hours, and gas adsorption (pp. 16798 to 16799).
Evidence fitness
This is a materials or analytical chemistry paper in which bismuth is a component of an engineered material. It does not support dietary exposure or toxicity claims for bismuth, and no bismuth was measured in food, water, feed, soil or human or animal tissue.
Limitations
Cytotoxicity was tested in one cell line for 24 hours on an engineered material, which cannot be extended to dietary bismuth. The introduction’s statement about rat median lethal doses is background drawn from other work.
Related evidence
Update history
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