Importance of Arsenic Speciation in Populations Exposed to Arsenic in Drinking Water

Overview

This source page is a mechanical bulk-ingest record for a PDF in the Heavy Metal Index raw corpus. It preserves source-level identity, routeable analyte and product scope, and the exact extracted numeric lines that justify that scope, for later human or fresh-context audit. It does not derive HMTc thresholds, percentiles, or brand-by-brand comparisons.

Author, year, and title are taken from the Crossref record for the DOI, not scraped from the PDF text.

Key numbers

Each analyte named in metals: is listed below with the measurement-bearing lines that caused it to be asserted. Lines are copied from the verified extraction and retain the source units and wording where legible. An analyte with no lines here would not appear in the frontmatter.

tAs

• water arsenic concentrations less than 3 µg/L, which is less than the New Jersey
• arsenic MCL of 5 µg/L, were recruited as comparison subjects.
• with known total arsenic (306 µg/L) and “non-dietary” (inorganic-related) arsenic
• required to have home water arsenic concentrations less than 5 µg/L to participate
• The mean untreated water arsenic concentrations were 45 ± 4.5 µg/L for the Ex-
• centrations exceeding the New Jersey arsenic drinking water standard of 5 µg/L,
• and 94% of these subject’s water arsenic levels exceeded the U.S. Environmental
• guideline level of 10 µg/L. All of the comparison subjects had water arsenic con-
• Shown in Figure 2 are the geometric mean total arsenic and inorganic-related
• data show that it took almost 3 weeks for subject 1902’s urine total arsenic level to
• Figure 6. Total urinary arsenic after 80 µg/L arsenic in water and dietary arsenic
• average 13.9 µg/g of creatinine higher than the inorganic-related arsenic concen-

Methods (brief)

• icity by AsIII, AsV, Dimethylarsinous Acid (DMAIII), Monomethylarsenate (MMAV),
• Dimethylarsinate (DMAV), Arsenobetaine (AsB), Arsenocholine (AsC), and the ar-
• DMAIII Dimethylarsinous acid (CH3 )2 AsOH(((CH3 )2 As)2 O) Metabolite
• DMAV Dimethylarsinate (CH3 ) 2 AsO(OH) Metabolite &
• the variety of mushroom. They can include AsIII, AsV, AsB, AsC, MMAV, and DMAV
• metabolized in humans by reduction and methylation to MMAV, MMAIII, DMAV,
• and DMAIII (Aposhian et al. 2000a; Loffredo et al. 2003; Vahidnia et al. 2007; Vahter
• 2002). Arsenosugars are metabolized mainly to DMAV, but also to MMAV and other
• scallops, the arsenic may be in the more toxic DMA species because the arsenosugars
• in seaweed or scallops are metabolized in humans to DMA (Le et al. 1994).
• arsenic analysis was performed by inductively coupled mass spectrometry (ICP-MS)
• The measurement of arsenic via ICP-MS depends on detection of its ion, which
• eration ICP-MS (HG-ICP-MS). The goal of this method is to separate the inorganic
• MMAIII, DMAV, and DMAIII) from higher molecular weight arsenic species commonly
• found in seafood and fish (AsB, AsC, and arsenosugars). Briefly, in HG-ICP-MS, sam-
• this method, AsV, AsIII, MMAV, MMAIII, DMAV, and DMAIII are all converted with
• MMAV + DMAV + DMAIII (inorganic-related arsenic); and then quantification of
• found that urinary DMA remained elevated for up to 6 days after ingestion of fish,

Implications

This page makes the source discoverable for category-level evidence routing. Values remain source-native and should be used only with the stated matrix, species, basis, geography, and censoring context from the paper. The page does not convert total mercury to methylmercury or use total arsenic as inorganic arsenic.

Wiki pages this source may touch

• Fish — marine, predatory (tuna, swordfish, shark, king mackerel)
• Fish — marine, non-predatory (sardines, anchovies, salmon, cod)
• Shellfish (shrimp, crab, lobster, clams, oysters, mussels)
• Seaweed/kelp foods (nori, wakame, kombu, dulse — as food products)
• Arsenic

Verification notes

• Identity check: DOI, raw handle, cite-key, and SHA-256 were compared against existing wiki/sources/ pages before creation.
• Provenance: first author and publication year resolved from Crossref for DOI 10.1080/10807039.2012.722824. PDFs whose DOI does not resolve are skipped, not given a fallback key.
• Full-PDF read: pdftotext -layout was run twice and the extraction hashes compared before the page was written.
• Analyte scope: each metal is asserted only where its spelled-out name appears on a line carrying a measurement. Element symbols alone never assert an analyte.
• Brand firewall: the worker skips PDFs whose numeric lines appear brand-sensitive; this page contains category-level or species-level evidence only.
• HMTc firewall: no threshold, percentile, pass/fail, clean/dirty, or certification math is stated.

Update history

The five most recent substantive edits to this page, classified major (evidence or structure moved), correction (a published value or statement was wrong and has been fixed), or minor (narrative rewritten without changing the underlying evidence). Each description is derived from what the edit did to this page; the linked commit is the authoritative record, routine regeneration passes are excluded, and the full version history lives in git. When DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.