Lo Dico et al. 2015 - ICP-MS metals in infant formula

Lo Dico and colleagues validated an ICP-MS method for simultaneous determination of arsenic, copper, chromium, selenium, tin, cadmium, antimony, and lead in infant formulas after microwave-assisted digestion. The paper is routeable for infant-formula occurrence evidence because it includes infant formula sample results as part of method validation. It reports total elements and does not provide arsenic or chromium speciation.

Key numbers

  • Target analytes: As, Cu, Cr, Se, Sn, Cd, Sb, and Pb.
  • The method used microwave-assisted digestion followed by ICP-MS.
  • Calibration and validation tables report concentration levels from 0.001 to 50 µg/L for standards and include LOD/LOQ information.
  • The source includes infant formula sample measurements and recovery, repeatability, and within-laboratory reproducibility at three concentration levels.

Methods (brief)

The paper is primarily a method-validation source using infant formula matrices. It supports occurrence extraction only where sample-result tables are used, and it supports testing-method context more strongly than broad market benchmarking.

Implications

Certification: Useful for infant-formula source coverage and method validation, but standards-pool admission should require extraction of the actual sample table and basis conversion.

Courses: Good example of microwave digestion plus ICP-MS for infant formula.

App: Can provide infant-formula metals context after structured extraction.

Wiki pages this source may touch

Verification notes

The same DOI was fetched under formula and infant-formula Cd, Pb, Sn, and tAs gaps. This page is the canonical page for those duplicate paths. Arsenic and chromium are total element measurements, not iAs or Cr(VI).

Page history

The five most recent substantive edits to this page. The full version history lives in git; when DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.

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6eea0b92026-05-29ingest auto-fetched 2026-05-29 0000 batch 1: 9 source pages