Gardner and colleagues describe patients allergic to methylchloroisothiazolinone/methylisothiazolinone in moist toilet paper. Four patients were using that product. The paper is a preservative case series. A patch-test mention of potassium dichromate 0.25 percent is a test-substance concentration, not chromium in the toilet paper. A positive cobalt chloride reaction without a printed product concentration is not a cobalt measurement in the product.
Key numbers
No heavy-metal concentration in the product is reported. Potassium dichromate 0.25 percent, if printed, is the patch-test preparation.
Methods (brief)
Clinical observation. Archives of Dermatology, 2010.
Evidence fitness
The cases support a preservative-allergy note for moist toilet paper. They do not support metal contamination, and they do not route to baby wipes.
Limitations
Small case series. Patch-test concentrations are not product assays.
Related evidence
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