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Heavy Metal Index

Methylisothiazolinone allergy in a dermatology clinic, including exposure from wipes

Jennifer Cahill, Ryan Toholka, and Rosemary Nixon report their clinic’s methylisothiazolinone patch-test rates and list disposable wipes among exposures.

Jennifer Cahill, Ryan Toholka, and Rosemary Nixon report their clinic’s methylisothiazolinone patch-test rates and list disposable wipes among exposures. The DOI printed on the letter is 10.5694/mja13.10946. A different Cahill paper in Pediatrics is not this document.

Key numbers

Relevant methylisothiazolinone reactions were 3.5% (15/428) in 2011, 8.4% (38/454) in 2012, and 11.3% (40/353) to November 2013. These are preservative allergy rates, not metal concentrations.

Methods (brief)

Baseline patch-test series in one Australian clinic.

Evidence fitness

The rates describe preservative allergy. They do not describe metals in wipes.

Limitations

One-page letter. Denominators are patch-test patients, not wipe products assayed for metals.

Update history

No substantive edit history is available in this build. The full commit record is available in git.