Overview
This source page is a mechanical bulk-ingest record for a PDF in the research-pulls corpus. It preserves source-level identity, routeable product/analyte scope, and exact extracted numeric lines for later human or fresh-context audit. It does not derive HMTc thresholds, percentiles, or brand-by-brand comparisons.
Key numbers
The worker extracted the full PDF text with layout preservation twice and compared extraction hashes before commit. The following lines are copied from numeric/table-bearing regions of the PDF and retain the source units and wording where legible:
- neurodegenerative diseases in people over 65 years of age ranges
- lactate via the glycolytic pathway, which provides an energy coordinate Zn2+ , thus maintaining a stable conformation of the
- to form transcriptional regulatory complexes. ZBTB7A proteins, as transcription factors, play a wide range of critical roles in organisms, involving
- formation of a wide range of tumors by regulating the P53, factor (VEGF)) (Leng et al., 2019). Therefore, ZBTB7A plays an
- although the brain is only approximately 2% of body mass, lactate via lactate dehydrogenases (LDHs).
- it consumes 20–25% of total glucose consumption (Magistretti When a cell breaks down glucose in a specific way in the
- through aerobic glycolysis, which has been shown to be the only fructose-2,6-bisphosphate, which can act as a metastable activator
- neurons. Meanwhile, astrocytes predominantly express GLUT1 on Database to predict that ZBTB7A has potential binding sites in
- neurodegenerative diseases The Relative Profile Score threshold was set to 80% to predict the
- MCT-4) in astrocytes, affects the glycolytic network, and reduces the progression of a variety of diseases (Table 1). Natural product
- addition, ZBTB7A-mediated abnormalities in astrocyte glycolysis synthesized drugs in the treatment of a wide range of diseases (Bui
- TABLE 1 Therapeutic agents targeting ZBTB7A.
- Danial, N. N., Gramm, C. F., Scorrano, L., Zhang, C. Y., Krauss, S., Ranger, A. M., and electrophysiological remodeling in the heart. J. Am. Heart Assoc. 13:e033676.
Methods (brief)
- 2024). Xu et al. (2005) reported that cystatin C (Cys C) stimulates JASPAR 2024 database,1 are collected from the literature, supported
- De Jesus, A., Keyhani-Nejad, F., Pusec, C. M., Goodman, L., Geier, J. A., Stoolman, J. S., splicing of PKM. Int. J. Mol. Sci. 24:5162. doi: 10.3390/ijms24065162
- promote neurite outgrowth on an inhibitory matrix. Int. J. Mol. Sci. 24:6058. doi: Khakh, B. S., Beaumont, V., Cachope, R., Munoz-Sanjuan, I., Goldman, S. A., and
- Pucino, V., Certo, M., Bulusu, V., Cucchi, D., Goldmann, K., Pontarini, E., et al. (2019).
Implications
This page makes the source discoverable for category-level evidence routing. Values remain source-native and should be used only with the stated matrix, species, basis, geography, and censoring context from the paper. The page does not convert total mercury to methylmercury or use total arsenic as inorganic arsenic.
Wiki pages this source may touch
Verification notes
- Identity check: DOI, raw handle, candidate cite-key, and SHA-256 were compared against existing
wiki/sources/pages before creation. - Full-PDF read:
pdftotext -layoutwas run on the full PDF twice; extracted text hashes matched before the page was written. - Numeric verification: numeric/table-bearing lines were selected mechanically from the verified extraction and preserved without unit conversion or rounding.
- Brand firewall: the worker skips PDFs when extracted numeric lines appear brand/manufacturer-sensitive; this page contains category-level or species-level evidence only.
- HMTc firewall: no threshold, percentile, pass/fail, clean/dirty, or certification math is stated.
Update history
The five most recent substantive edits to this page, classified major (evidence or structure moved), correction (a published value or statement was wrong and has been fixed), or minor (narrative rewritten without changing the underlying evidence). Each description is derived from what the edit did to this page; the linked commit is the authoritative record, routine regeneration passes are excluded, and the full version history lives in git. When DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.