Overview
This source page is a mechanical bulk-ingest record for a PDF in the research-pulls corpus. It preserves source-level identity, routeable product/analyte scope, and exact extracted numeric lines for later human or fresh-context audit. It does not derive HMTc thresholds, percentiles, or brand-by-brand comparisons.
Key numbers
The worker extracted the full PDF text with layout preservation twice and compared extraction hashes before commit. The following lines are copied from numeric/table-bearing regions of the PDF and retain the source units and wording where legible:
- groups on proteins. The toxicity As(V) results from its of approx. 2 mg/kg, and the toxic and lethal value is ap-
- reduction to As(III) in the human body (1–3). Among prox. even 13 mg/kg. The half-life of As is 7–10 h, and
- Arsenic occurs mainly in the Earth’s crust (2.5 ppm), in- of cancer and often saving lives – in the latter case, when
- cluding hypotension, heart failure, cardiac arrhythmia, counting for >50% of estimated total deaths. The higher
- fect of high levels of As in groundwater (>300 μg/l) on repolarization on the ECG) (4,12). According to the au-
- even at high exposures (As in drinking water at >50 μg/l) tions with dietary factors, genetics, and personal habits
- of As (4,32,33). Meanwhile, another systematic review by tion (13,16). Increased vascular stiffness, resulting from
- (up to 147.7 μg/l), was associated with greater monthly As poisoning alone can result in hemolytic anemia,
- sure (PP). Another meta-analysis showed a potential link erate exposure alone, with exposure M = 19.3 μg/l and
- lial biochemical mediators. The effects of As may reflect been chronically exposed to As (≥10 μg/l) had more
- tion (6). Meanwhile, Serbia showed an incidence of acute tion affects numerous physiological or pathophysiolog-
- posure (1–80 μg/l), where the former had a CVD inci- thase is endothelial dysfunction resulting from the onset
- posure to As (i.e., >100 μg/l) with CVD, and mainly heart Although As stimulates nicotinamide adenine dinucle-
- the detectable level by almost one-fifth (78). Ingesting ■ providing extensive education and raising awareness
- consumed water with As content >10 μg/l. The WHO’s water,
- proposed limit in water is 10 μg/l (1,4,6,16,18). Mean- ■ it is noteworthy that the association between prenatal
- vised its stance, recommending a max level of ≤10 μg/l in other biomarkers can be used preventively or as a po-
- Table 1. Recommendations for future research for health protection and environmental action regarding exposure to arsenic (As) (80)
- tions (<50 μg/l) and even fewer to lower concentrations Constant exposure and acute poisoning most often
- world (Table 1). Even in the case of the smallest and short-term expo-
- and arsenic concentrations accounted for 3–19% of Liaw J, et al. Acute myocardial infarction mortality in com-
Methods (brief)
- https://medpr.imp.lodz.pl/en https://doi.org/10.13075/mp.5893.01622
- long-term exposure to As at the individual level in different groups. Reliable biomarkers with appropriate references to the sample should be
- high levels of As exposure and relatively small sample pressure (DBP). It worsens the healing of gangrene
- emphasize in their analysis that the collected epidemio- at the microRNA (miRNA) stage) and induction of in-
- kinase pathway), etc. (3). Conversion from As(V) to trivalent metabolites, MMAIII and DMAIII, have been
- as interferes with DNA repair processes, chromosome ab- ■ dimethylarsinic acid ((CH₃)₂AsO(OH), DMAV),
- normalities, epigenetic regulation, and apoptosis (2,5,11, ■ dimethylarsenous acid ((CH₃)₂AsOH, DMAIII),
-
- Davignon J, Ganz P. Role of endothelial dysfunction in athero- 57. Monrad M, Ersboll AK, Sorensen M, Baastrup R, Han
-
- Ersbøll AK, Monrad M, Sørensen M, Baastrup R, Hansen 63. Newman JD, Navas-Acien A, Kuo CC, Guallar E, Howard BV,
Implications
This page makes the source discoverable for category-level evidence routing. Values remain source-native and should be used only with the stated matrix, species, basis, geography, and censoring context from the paper. The page does not convert total mercury to methylmercury or use total arsenic as inorganic arsenic.
Wiki pages this source may touch
- Fish — marine, predatory (tuna, swordfish, shark, king mackerel)
- Fish — marine, non-predatory (sardines, anchovies, salmon, cod)
- Shellfish (shrimp, crab, lobster, clams, oysters, mussels)
- Mercury
- Cadmium
- Lead
- Arsenic
- Nickel
- Tin
- Chromium
Verification notes
- Identity check: DOI, raw handle, candidate cite-key, and SHA-256 were compared against existing
wiki/sources/pages before creation. - Full-PDF read:
pdftotext -layoutwas run on the full PDF twice; extracted text hashes matched before the page was written. - Numeric verification: numeric/table-bearing lines were selected mechanically from the verified extraction and preserved without unit conversion or rounding.
- Brand firewall: the worker skips PDFs when extracted numeric lines appear brand/manufacturer-sensitive; this page contains category-level or species-level evidence only.
- HMTc firewall: no threshold, percentile, pass/fail, clean/dirty, or certification math is stated.
Update history
The five most recent substantive edits to this page, classified major (evidence or structure moved), correction (a published value or statement was wrong and has been fixed), or minor (narrative rewritten without changing the underlying evidence). Each description is derived from what the edit did to this page; the linked commit is the authoritative record, routine regeneration passes are excluded, and the full version history lives in git. When DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.