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Heavy Metal Index

Exposure to arsenic and cognitive

Source

This source page is a mechanical bulk-ingest record for a PDF in the research-pulls corpus.

Page snapshot
Cited by5 pages
Metals measured3
Evidence tierB
Year2025

Overview

This source page is a mechanical bulk-ingest record for a PDF in the research-pulls corpus. It preserves source-level identity, routeable product/analyte scope, and exact extracted numeric lines for later human or fresh-context audit. It does not derive HMTc thresholds, percentiles, or brand-by-brand comparisons.

Key numbers

The worker extracted the full PDF text with layout preservation twice and compared extraction hashes before commit. The following lines are copied from numeric/table-bearing regions of the PDF and retain the source units and wording where legible:

  • to April 2024, without language restrictions to capture a wide range of international
  • sis. This has been reported in Table 1.
  • descriptive (Bangalacombo, water is 46% using functioning level, which shows
  • et al. 2001 nity based- of age attending ele- the CDC, 57.6% of spectrophotometric Longterm memory and atten- (51.3)
  • Table 1. (Continued)
  • Ghosh S B India School based Children studying in 142 As (ppm) in of UV–Visible Water quality of control group 9.6 ± 2.3 Male – 66 Low PLOS ONE
  • et al. 2017 Cross-sectional the 3rd and 4th stan- high-exposure group spectrophotometer clearly revealed that mean (46.3)
  • Nahar M N Bangla- School based Adolescents between 312 The mean As concen- Inductively coupled The IQ in the high-(As)u group Not available Male - 138 Moderate
  • 2011 Cross-sectional old, living near a metal median (interquartile atomic absorption quartile of UAs, those in the (55.5)
  • Table 1. (Continued)
  • Von Ehr- India Commu- Children age 5 to 351 Arsenic concentrations Flow injection Increasing tertiles of urinary Median age -9 Male – 190 Moderate PLOS ONE
  • arsenic reductions between 12% and
  • exposure in water was 20%, but the confidence inter-
  • 0–9 g/L for 56% of vals were broad.
  • Amador D nity based- lived in the area since ± 1.3 μg/L); Salitral Spectrophotometer fluoride levels in urine and reported
  • et al. Cross-sectional birth and who were (As 169 ± 0.9 μg/L) with hydride system children’s Performance, Verbal,
  • 194 ± 1.3 μg/L) ing for confounders (β values =
  • 2007 based- Cross and 12 years of age high-arsenic groups atomic fluorescence from a mean of 105 in the control
  • μg/L and 190 μg/L, high-arsenic group. The reductions
  • et al.2004 desh based- Cohort children of age 9.5 to high concentrations atomic absorption levels > 50 μg/L achieved signifi-
  • a mean of 117.8 μg/L Full-Scale scores compared to
  • across the 196 wells children with levels < 5.5 μg/L.
  • Table 1. (Continued)
  • study school districts are tration across the 272 coupled plasma water, at or above 5 μg/L, was
  • was 9.88 μg/L. (HR-ICP-MS). mance on intelligence tests
  • study 6.25 years of age whose water ranged from 0.1 (GFAA) were associated with lower
  • of author was 120.1 μg/L non-verbal abilities.
  • al.2017 nity based- children aged 6–15 years nic (μg/L) Median development and IQ scores cohort (mean age reported
  • borhoods in Arica, with (11–26) levels of heavy metal contami- cohort (mean
  • Hamadani Bangla- Community Infants born between 2,260 70% of the tube wells High-pressure liquid Early life exposure to arsenic, par- 5 years 1,175/1,085 Low
  • tested 7 months, 1.5 10 μg/L, which was scores specifically in girls, suggest-
  • 2018 Cross-sectional who regularly attended median UAs concen- measured based on association between urinary
  • study the school from July tration was 11.9 μg/l the urinary total arsenic and general cog-
  • 2009 and August 2013 (range = 1.4–93.9). concentration of iAs, nitive abilities measured by the
  • Table 1. (Continued)
  • Wang et China Community school-aged children 148 The mean water Hydride generation Prenatal low-level As exposure 89.90 ± 3.77 71/77 High PLOS ONE
  • 190 μg/L in the con- (HG-AFS) (PIQ) and verbal intelligence
  • Zhou et China Community school-aged children 296 0.5–193.09 μg/L in Inductively coupled Arsenic did not show sig- NR 170/126 High
  • Vaidya et India Community participants aged 6 to 1,014 9.65 (9.40) μg/L in Atomic absorption Sparse-partial least squares 14.86 (4.79) 589/425 Low
  • Rosado et Mexico School based children 6–8 years 602 58.1 ± 33.2 µg/L in Atomic Absorption Linear and logistic regressions 83.4 ± 4.4 319/272 Moderate
  • Table 1. (Continued)
  • Ossa et Colombia Commu- Colombian children 70 1.96 ± 2.73 µg/L in atomic absorp- Correlation analyses found, 12.2 ± 2.0 34/36 Moderate PLOS ONE

Methods (brief)

  • due to differences in study design, sample size, exposure levels, or genetic and environmental
  • information about study population, research setting, sample size, baseline characteristics, and
  • Selection criteria included aspects like the representativeness of the sample and ascertainment
  • Author Country Study design Population Sample Exposure Method used Outcome Mean age Gender Risk of bias
  • al. 2012 desh Cross-sectional of 8 to 11 who had atomic absorption significantly related to mathe- (47.1)
  • Abbas S et Pakistan Commu- School going adult Not In experimental group Atomic absorption In all the three sites the average Not available Not High
  • study Kamal chisti town, Atomic absorption the relationship of health status
  • Calderon J Mexico Commu- Children 6 to 9 years 80 According to Atomic absorption Verbal comprehension, 7.61 ± 0.8 Male – 41 Moderate
  • Author Country Study design Population Sample Exposure Method used Outcome Mean age Gender Risk of bias
  • 2011 Cross-sectional old, living near a metal median (interquartile atomic absorption quartile of UAs, those in the (55.5)
  • Author Country Study design Population Sample Exposure Method used Outcome Mean age Gender Risk of bias
  • Rocha- Mexico Commu- Children who had 132 Moct- ezuma (As 5.8 Atomic Absorption Inverse associations between 8.3 ± 1.1 Not High
  • et al.2004 desh based- Cohort children of age 9.5 to high concentrations atomic absorption levels > 50 μg/L achieved signifi-
  • Author Country Study design Population Sample Exposure Method used Outcome Mean age Gender Risk of bias
  • included children in the study mass spectrometry associated with lower perfor-
  • was 9.88 μg/L. (HR-ICP-MS). mance on intelligence tests
  • et al. 2007 desh based- Cohort children of 5.75 years and tions in the tube well atomic absorption exposure from drinking water
  • MMA and DMA. Woodcock-Muñoz tests.

Implications

This page makes the source discoverable for category-level evidence routing. Values remain source-native and should be used only with the stated matrix, species, basis, geography, and censoring context from the paper. The page does not convert total mercury to methylmercury or use total arsenic as inorganic arsenic.

Wiki pages this source may touch

Verification notes

  • Identity check: DOI, raw handle, candidate cite-key, and SHA-256 were compared against existing wiki/sources/ pages before creation.
  • Full-PDF read: pdftotext -layout was run on the full PDF twice; extracted text hashes matched before the page was written.
  • Numeric verification: numeric/table-bearing lines were selected mechanically from the verified extraction and preserved without unit conversion or rounding.
  • Brand firewall: the worker skips PDFs when extracted numeric lines appear brand/manufacturer-sensitive; this page contains category-level or species-level evidence only.
  • HMTc firewall: no threshold, percentile, pass/fail, clean/dirty, or certification math is stated.

Update history

The five most recent substantive edits to this page, classified major (evidence or structure moved), correction (a published value or statement was wrong and has been fixed), or minor (narrative rewritten without changing the underlying evidence). Each description is derived from what the edit did to this page; the linked commit is the authoritative record, routine regeneration passes are excluded, and the full version history lives in git. When DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.

CommitDateChangeDescription
b01ec52c2026-08-04major2 sections added
d49e450f2026-08-03major5 sections added; narrative text revised