Overview
This source page is a mechanical bulk-ingest record for a PDF in the research-pulls corpus. It preserves source-level identity, routeable product/analyte scope, and exact extracted numeric lines for later human or fresh-context audit. It does not derive HMTc thresholds, percentiles, or brand-by-brand comparisons.
Key numbers
The worker extracted the full PDF text with layout preservation twice and compared extraction hashes before commit. The following lines are copied from numeric/table-bearing regions of the PDF and retain the source units and wording where legible:
- median effective concentration (EC50 ) of MeHg in RIN-m5F cells was approximately 2 µM,
- 99.3 ± 3.3% of control). These results indicate that MeHg is capable of inducing cytotoxicity,
- 99.3 ± 3.3% of control). These results indicate that MeHg is capable of inducing cytotoxi-
- induced a depolarization of MMP (64.3 ± 2.8% of control; p < 0.05), and a more significant
- loss was observed after 24 h treatment (18.3 ± 1.1% of control; p < 0.05). Treatment with
- mean caspase-3,
- control; mean 0.05± SD of six to MeHg
-
- Discussion mean ± SD of six independent experiments assayed in triplicate. * p < 0.05 compared to vehicle
- with a MeHg concentration of approximately 2 mg/kg was associated with an increased
- higher mercury exposure at baseline was 2 mg/kg was
- association between higher blood mercury levels (0.5–86.8 µg/L) and defective pancreatic
- subjected to electrophoresis on 10% (w/v) SDS-polyacrylamide gels and transferred to
- PBST (PBS, 0.05% Tween-20) containing 5% nonfat dry milk. After blocking, the membranes
- p-Akt, JNK-1, ERK1/2, p38, Akt, and β-actin in 0.1% PBST (1:1000) for 12–16 h at 4 ◦ C.
- After 3 additional washes in 0.1% PBST (15 min each), the respective HRP-conjugated
- secondary antibodies were applied (1:2500 in 0.1% PBST) for 1 h at 4 ◦ C. The antibody-
- mannitol, 25 mM MOPS (pH 7.8), 1 mM EGTA, 8 mM cysteine, and 0.1% (w/v) bovine
- Data are presented as mean ± standard deviation (SD) of at least 4 independent
Methods (brief)
- stimulate insulin secretion, and the supernatant was immediately collected and stored at
- −20 ◦ C (25,27). To measure the amount of insulin secretion, aliquots of samples were as-
- according to the manufacturer’s instructions. Each sample (2 µL cDNA) was then tested
- was calculated for each individual sample.
Implications
This page makes the source discoverable for category-level evidence routing. Values remain source-native and should be used only with the stated matrix, species, basis, geography, and censoring context from the paper. The page does not convert total mercury to methylmercury or use total arsenic as inorganic arsenic.
Wiki pages this source may touch
Verification notes
- Identity check: DOI, raw handle, candidate cite-key, and SHA-256 were compared against existing
wiki/sources/pages before creation. - Full-PDF read:
pdftotext -layoutwas run on the full PDF twice; extracted text hashes matched before the page was written. - Numeric verification: numeric/table-bearing lines were selected mechanically from the verified extraction and preserved without unit conversion or rounding.
- Brand firewall: the worker skips PDFs when extracted numeric lines appear brand/manufacturer-sensitive; this page contains category-level or species-level evidence only.
- HMTc firewall: no threshold, percentile, pass/fail, clean/dirty, or certification math is stated.
Update history
The five most recent substantive edits to this page, classified major (evidence or structure moved), correction (a published value or statement was wrong and has been fixed), or minor (narrative rewritten without changing the underlying evidence). Each description is derived from what the edit did to this page; the linked commit is the authoritative record, routine regeneration passes are excluded, and the full version history lives in git. When DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.