ATSDR 2024 — Toxicological Profile for Mercury

Summary

The October 2024 ATSDR Toxicological Profile for Mercury is the current US comprehensive synthesis covering elemental mercury (Hg⁰), inorganic mercury salts, and methylmercury (the dominant species in seafood). Each species has distinct toxicity profiles: elemental mercury vapor is primarily a neurotoxicant via inhalation (occupational exposure, dental amalgam); inorganic mercury salts are primarily nephrotoxic via oral exposure; methylmercury is the dominant developmental neurotoxicant relevant to dietary risk through fish and seafood consumption. ATSDR derives MRLs separately for each species and route in this profile.

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