p4-batch13-2026-05-13

P4 Batch 13 — Ingest Report (2026-05-13)

Positions 4368–4567 of the P4 manifest, sorted by (-year, handle). First handle: FM_9999012 (g1). Last handle: FM_8735667 (g4). Year band: 2021–2023 with FM-number distribution across that cohort.

Four parallel background agents, 50 handles each.

Summary

Group	Positions	Commit	Pages	FP	FP rate
g1	4368–4417	swept into g2 8c1225e	12	38	76%
g2	4418–4467	8c1225e	7	43	86%
g3	4468–4517	5028098	11	39	78%
g4	4518–4567	509f5e7	5	45	90%
Total	4368–4567		35	165	82.5%

Note on g1: g1 wrote all 12 source pages successfully but hit a stale .git/index.lock from an interrupted pre-commit hook run, leaving its files staged but uncommitted. The lock cleared naturally before g2 committed; g2’s pre-commit hook picked up g1’s 12 staged files along with g2’s own 7, producing a 20-file commit (8c1225e, labeled as g2 by message). All g1 pages are in git.

Source pages by group

G1 — 12 pages (positions 4368–4417, FM_9999012–FM_10140520)

1. chen2023-heavy-metals-ibd — Frontiers Public Health CC BY; review of Pb/Mn/As/Cd/Hg in IBD pathogenesis via gut barrier disruption, dysbiosis, oxidative stress; directly relevant to microbiome pages
2. limmer2023-sr-xrf-rice-grain — Journal of Synchrotron Radiation; SR-µXRF spatial mapping of As, Zn, Cu, Mn in rice grain cross-sections, n=50, US field trials; bran-layer As concentration gradient documents the milling mitigation rationale at sub-millimeter resolution
3. bae2023-tuna-heavy-metals-korea — CC BY-NC; MeHg 560 ppb, Pb 34 ppb, Cd 14 ppb, tAs 1,460 ppb in 31 Korean commercial tuna; 9.7% exceeded Korean MeHg MRL
4. abdelnaby2022-lead-cadmium-milk — CC BY; Pb 237 ppb, Cd 41 ppb in 35 Egyptian milk samples, both well above EU limits; chitosan adsorption reduced Pb 55–70%; natural adsorbent mitigation data
5. xie2023-metal-mixtures-nafld-nhanes — Frontiers Public Health CC BY; 13-metal urinary mixture vs NAFLD/liver fibrosis, NHANES 2003–2018 n=5,548; As, Cd, Pb highest-weighted in WQS and BKMR regression models
6. abdelgawad2023-chromium-rice-grain — Frontiers Plant Science CC BY; experimental Cr(VI) spiking in Egyptian rice, elevated CO2 reduced grain Cr 30–40%; experimental, not market-realistic concentrations
7. cao2023-lead-pakchoi-eps-bacteria — Frontiers Microbiology CC BY; EPS-producing bacteria reduced Pb in pakchoi 14.5–39.2% under field-realistic Chinese soil Pb levels
8. ahmed2023-trace-metals-tomato-wastewater — Environ Sci Pollut Res CC BY; wastewater-irrigated Cairo tomatoes, Pb ~360 mg/kg (unit ambiguity flagged), HQ >1 for multiple metals; extreme contamination scenario
9. jurowski2022-chromium-peppermint-tincture — CC BY; Cr 0.39–2.14 µg/L in Polish peppermint tinctures, well below Pharmacopoeia limits; speciation discussion Cr-III vs Cr-VI; 1-of-3 papers needed for peppermint/herbal-tinctures page
10. sonke2023-mercury-global-change — Ambio CC BY; global Hg biogeochemical cycling review, US$117B annual economic cost, climate warming projected to raise fish MeHg 10–30%
11. hampton2023-lead-game-meat-australia — Environ Sci Pollut Res CC BY; n=133 Australian game meat, quail 1,760 ppb Pb mean, venison 120 ppb, kangaroo 10 ppb; 86% quail and 53% venison exceeded AU 100 ppb threshold; 1-of-3 papers needed for game-meat page
12. cui2022-mercury-speciation-rice-china — ACS Environ Au CC BY; 464,368-grid model of tHg and MeHg in Chinese rice 2017; national median tHg 5.65 ppb, MeHg 1.30 ppb; 81.3% tHg from atmospheric deposition; Guizhou hotspot up to 238.6 ppb MeHg

G2 — 7 pages (positions 4418–4467)

13. nepper-davidsen2023-kelp-biomass-composition-nz — ICP-MS for tAs, Cd, Pb, tHg in Ecklonia radiata kelp, 12 NZ sites; mean tAs 49 ppm DW, Cd 1.2 ppm DW; significant temporal autocorrelation for As and Hg; iAs speciation absent
14. de-silva2023-industrial-waste-land-application-soil — B-tier systematic review; Cr, As, Pb, Ni, Cd pathways to agricultural soils from fly ash, tannery waste, foundry sand, red mud
15. pain2023-lead-pheasant-dogfood-uk — Ambio; Pb in commercial pheasant pet food UK, n=193 packages, mean 220.99 ppm DW (shot-free), 77% exceeded EU MRL; documents lead-shot ammunition fragmentation in pheasant carcasses commercially sold as pet food
16. romero-crespo2023-trace-elements-crops-ecuador-mining — Ecuador gold mining region; tAs up to 12.50 mg/kg FW in lettuce, Cd up to 1.64 mg/kg FW in turnips; 67% As and 78% Cd exceeded FAO/WHO MPLs; Pb below LOD in all food samples
17. zakrzewska2023-cadmium-soil-micp-parsley — Frontiers Plant Science; Ochrobactrum MICP treatment reduced soil Cd bioavailability 27–65% and parsley shoot Cd ~86%
18. abedi2023-arsenic-mercury-hen-eggs-iran — BMC Public Health; mean tAs 0.79 µg/kg WW, tHg 0.18 µg/kg WW in Tehran commercial eggs, n=84; ILCR for As 4.35×10⁻⁴ above 10⁻⁴ threshold despite THQ <<1
19. wang2023-toxic-metals-daily-diet-ningxia — ICP-AES multi-food dietary survey, industrial northern Ningxia China, n=187 samples; total HI 5.61, Pb in beans 60% over-standard; cereals highest HI contributor

G3 — 11 pages (positions 4468–4517)

20. inada2023-herbal-medicine-heavy-metal-regulations — comparison of Pb, Cd, Hg, As limits across 9 pharmacopoeias (JP, EU, USP, ChP, KP, TaiwanP, IP, BP, WHO); documents regulatory harmonization gaps for herbal medicines across jurisdictions
21. sitek2022-cd-toxicity-antioxidant-vitamins — CC BY review; rice, potatoes, and wheat account for 40–60% of European dietary Cd; antioxidant vitamins (C, E, D) documented as partial protective interventions
22. weyde2023-gestational-metals-cerebral-palsy — Norwegian MoBa cohort case-control, n=1,226; tHg, Pb, As in gestational blood; null association with cerebral palsy at low Norwegian exposure levels
23. abebe2023-awash-river-heavy-metals — 205 water samples, Awash River and Lake Beseka, Ethiopia; As exceeded WHO limits in 57% of samples; relevant to Ethiopian irrigation water and downstream crop contamination
24. cardoso2023-mercury-portuguese-coast-seafood — seasonal tHg in bivalves from 3 Portuguese estuaries; bivalves <0.5 µg/g ww all sites; moderate environmental risk index in Ria de Aveiro autumn; seasonal pattern confirmed
25. molina2023-mercury-buenaventura-bay — tHg in Buenaventura Bay sediments, Colombia; organic matter and salinity predict accumulation; benthic food-chain pathway documented; relevant to Pacific coast seafood sourcing
26. begum2023-rawal-lake-water-quality — CC BY; Rawal Lake, Pakistan; Cd and Pb exceed WHO limits in Bari Imam and Rumli tributaries feeding the primary Islamabad drinking water reservoir
27. ashley-martin2022-ias-biomonitoring-pregnancy — Health Canada review; iAs speciation across 9 biological matrices in pregnancy; HPLC-ICP-MS speciation; dietary iAs sources for low-drinking-water-exposure populations include rice, vegetables, seafood; strong speciation methodology reference
28. gupta2023-rice-ash-bangladesh-arsenic-cadmium — Meharg group Bangladesh field trials; household rice-straw ash as fertiliser; null effect on grain iAs, DMA, and Cd; confirms region and season dominate over this common smallholder input
29. mukhi2022-heavy-metals-food-packaging — CC BY; India, ICP-OES for 13 food and drug packaging types; As above EU limits in all 13 samples; vanadium in 10 of 13; packaging as a previously undercharacterized contamination transfer pathway
30. huang2023-ml-rice-cadmium-soil — SVM model R²=0.87 for predicting rice grain Cd from soil properties in Xiangtan, Hunan; 53.9% of samples exceed China MPL; liming to pH 6.5 reduces exceedance rate from 36.5% to 2%

G4 — 5 pages (positions 4518–4567, FM_11502062–FM_8735667)

31. shaalan2024-nile-tilapia-heavy-metals-egypt — CC BY-NC-ND; ICP-OES for 8 metals in Nile tilapia muscle, Damietta branch and El-Rayah El-Tawfeeky canal, Egypt, n=120; El-Rayah values: Pb 33.4 mg/kg, Cd 2.3 mg/kg, Hg 10.4 mg/kg — extreme multi-metal co-elevation in high-pollution zone; HI>1 for habitual consumers across multiple metals
32. tasdivrik2025-drinking-water-heavy-metals-sivas-turkey — CC BY; ICP-MS for As, Cd, Zn, Mn, Cu in 5 drinking fountains, Şarkışla, Sivas, Turkey, 4 seasons; As 793–1,323 ppb (~80–130× WHO limit); geogenic Pliocene aquifer source; carcinogenic risk exceeds 1×10⁻⁴ for As
33. gholami2025-heavy-metals-corn-iran-khuzestan — CC BY; Pb, tAs, Cr in 50 corn and 50 soil samples, Khuzestan Province Iran; corn mean Pb 1,840 ppb, As 1,570 ppb, Cr 4,920 ppb, all well above Codex limits; industrial-zone proximity as contamination multiplier
34. zafarzadeh2025-heavy-metals-rice-sari-iran — CC BY; polarographic analysis for Pb, Cd, Cu, Zn in 144 rice samples from 16 mills, Sari, Mazandaran, Iran; all 144 samples exceed 0.2 mg/kg Pb limit; mean Pb 2,770 ppb; coastal hotspot 9,880 ppb (Caspian coastal aquifer influence)
35. melnyk2021-mercury-anadromous-fish-penobscot — CC BY; US EPA/ATSDR tHg in 6 anadromous fish species, Penobscot River, Maine, 75 composites 2017–2018; sea lamprey mean 628 µg/kg (max 1,040), exceeds safe consumption at any intake rate; alewife, shad, and herring safe at tribal 40 g/day advisory rate

New page proposals

No ingredient or product pages crossed the creation threshold (5 papers for ingredient, 3 for product-category) from this batch alone. Two candidates are building:

Game meat / venison — hampton2023 (Australian quail/venison/kangaroo) adds to pain2023 (pheasant pet food UK) from g2. These are 2 papers touching the lead-shot-in-game-meat contamination pattern, both with lead as the primary concern and ammunition fragmentation as the mechanism. Neither pain2023 (pet food) nor hampton2023 (wild harvest) fits cleanly into a single ingredient page; the appropriate scope is probably ingredients/game-meat.md or products/game-meat.md. Threshold not yet crossed; flag for next encounter.

Peppermint / herbal tinctures — jurowski2022 is the first paper to measure Cr in peppermint tinctures specifically. Threshold not crossed; flag for next encounter.

Synthesis threads

Mining-impacted freshwater fish (promoted candidate — 3 of 4 criteria met)

Batch 13 adds two relevant papers. shaalan2024-nile-tilapia-heavy-metals-egypt documents extreme multi-metal co-elevation (Pb 33.4 mg/kg, Cd 2.3 mg/kg, Hg 10.4 mg/kg) in Nile tilapia from an Egyptian industrial-effluent-impacted canal. This is industrial pollution rather than ASGM but confirms the multi-metal co-elevation pattern in contaminated freshwater fish beyond Hg alone, advancing criterion 2 (spans multiple metals). melnyk2021-mercury-anadromous-fish-penobscot adds US river Hg data for anadromous species from a historically contaminated New England system. Neither paper adds a third ASGM continent (Asia/Oceania) that would satisfy the geographic promotion trigger. The multi-metal criterion is now meaningfully better supported through industrial-zone analogues; update synthesis-proposals accordingly.

Dietary and herbal supplement Pb contamination (seeding — 1 of 4 criteria met)

Batch 13 adds inada2023-herbal-medicine-heavy-metal-regulations, a comparison of Pb, Cd, Hg, and As limits across 9 pharmacopoeias. This is a B-tier regulatory review, not a contamination measurement study, so it does not directly advance criterion 1. However, it provides regulatory-comparison context that strengthens the non-obvious framing (criterion 3): the Pb limits in different pharmacopoeias for herbal preparations vary from 5 ppm (EU) to 20 ppm (WHO); all of them are orders of magnitude lower than the 40,657 ppm thomas2024 case report. Inada2023 establishes that regulatory standards exist and that the thomas2024 capsule violated them by a factor of 8,131 under the most permissive limit cited. This is useful for the synthesis narrative but does not move the thread beyond 1 of 4 criteria met.

Metal mixtures and non-alcoholic fatty liver disease — new corroborating source for promoted page

xie2023-metal-mixtures-nafld-nhanes (Frontiers Public Health, CC BY, NHANES 2003–2018, n=5,548) is a strong corroborating source for the already-promoted combined-exposure-underprotection synthesis page. The study provides large-scale US epidemiological evidence that As, Cd, and Pb are the dominant contributors to a metal-mixture association with NAFLD and liver fibrosis, which extends the combined-exposure argument beyond neurological and developmental endpoints to metabolic liver disease. This does not warrant a separate synthesis page (the combined-exposure-underprotection page is the right home) but should be noted as a high-priority addition to that page’s source inventory on next synthesis pass.