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Exogenous Nitric Oxide (NO) Interferes with Lead (Pb)-Induced Toxicity by Detoxifying Reactive Oxygen Species in Hydroponically Grown Wheat (Triticum aestivum) Roots

Kaur et al.

Researched by
K. Pendergrass iD
Last updated: 2026-06-15
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Kaur et al. 2015 — Nitric oxide mitigation of lead toxicity in hydroponic wheat roots

This experimental paper studies whether exogenous nitric oxide can mitigate lead-induced oxidative stress in hydroponically grown wheat roots. It is an a2 mitigation and plant-toxicology source rather than a market occurrence paper. The paper is in scope because it evaluates a specific intervention against heavy-metal stress in an edible crop species and tracks the effect through oxidative-stress markers and membrane damage.

Key numbers

  • Wheat roots were exposed to lead at 50 and 250 uM, with sodium nitroprusside used as the nitric oxide donor at 100 uM.
  • Exposure experiments ran for 0-8 hours.
  • Nitric oxide supplementation reduced oxidative stress markers including malondialdehyde, conjugated dienes, hydroxyl ions, and superoxide anion.
  • Nitric oxide also decreased ion leakage and reduced histochemical evidence of membrane damage in wheat roots, especially up to 6 hours.

Methods (brief)

The study used hydroponically grown wheat roots exposed to lead alone and in combination with sodium nitroprusside. The authors evaluated oxidative-stress markers, antioxidant enzyme activity, ion leakage, in situ histochemical localization, and in vivo nitric oxide levels.

Evidence Fitness

Strong for a2 mitigation and mechanistic crop-stress context. It does not provide product occurrence data, but it is relevant to the mitigation literature because it tests a defined intervention against lead toxicity in a food crop.

Implications

Mitigation: This source belongs in agronomic mitigation because it evaluates a candidate protective mechanism against lead stress in wheat roots.

Supply-chain: It is also useful for pathway discussions on how heavy-metal stress affects crop physiology before harvest, even though the model is hydroponic rather than field-based.

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Page history

The five most recent substantive edits to this page. The full version history lives in git; when DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.

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ae6c1292026-07-01feat(auth): large login + role-based signup screens (design, burgundy)