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Heavy Metal Index

The effect of consuming bread contaminated with heavy metals on cardiovascular disease and calculating its risk assessment

Overview

This study paired urinary metals in 180 Hoveyzeh cohort participants with ICP-OES measurements of bread from Susangerd bakeries and estimated dietary risk. Table 4 pools all bread types into one summary. Mean arsenic, cadmium, lead and zinc exceeded the limits the authors cite.

Key numbers

  • Bread lead: mean 0.781 ± 1.12, range 0.13 to 2.63 mg/kg (Table 4).
  • Bread arsenic: mean 1.54 ± 0.64, range 0.64 to 2.27 mg/kg; cadmium mean 0.22 ± 0.09, range 0.02 to 0.29 mg/kg (Table 4).
  • Bread chromium is printed with a mean of 0.31 mg/kg above its maximum of 0.148 mg/kg (Table 4).

Methods (brief)

Bread was air-dried, oven-dried at 60 °C, ground, ashed at 450 °C, extracted with 4 M nitric acid and analyzed by ICP-OES. Detection limits are given only for the urine work. No certified reference material or recovery is reported for bread. Values are presumably dry weight.

Evidence Fitness

The bread data are a small, pooled summary with no sample count, and the chromium row is internally inconsistent. Arsenic at about 1.5 mg/kg is unusually high for bread. The cardiovascular findings are an association analysis, not concentration data. For bagels, crackers, pretzels, cinnamon rolls, cornbread, flour tortillas and toaster pastries this is a bread proxy only; none of those foods was measured.