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Heavy Metal Index

Quantitative Analysis of Heavy Metals in Unbranded Whitening Creams Sold in Karachi

Source

Alamgir and colleagues measured lead, nickel, chromium, total arsenic, and copper in 25 unbranded skin-whitening creams sold in Karachi, Pakistan.

Page snapshot
Cited by7 pages
Metals measured5
Evidence tierA
Year2022

Overview

Alamgir and colleagues measured lead, nickel, chromium, total arsenic, and copper in 25 unbranded skin-whitening creams sold in Karachi, Pakistan. Lead was the highest-concentration contaminant in the sample set, and every sampled cream exceeded the paper’s cited 1 ppm lead limit for cosmetics. The source is direct occurrence evidence for unbranded whitening-product matrices.

Key numbers

Table I reports concentrations in ppm for 25 skin-whitening cream samples.

MetalMeanMin-maxSD
Pb4.5682.11-9.121.847
Ni0.5460.12-1.210.274
Cr2.0131.13-2.680.421
As0.0220.005-0.0910.021
Cu0.4890.22-0.850.145

The highest lead value was 9.12 ppm and the lowest was 2.11 ppm. Chromium ranged from 1.13 to 2.68 ppm, nickel from 0.12 to 1.21 ppm, arsenic from 0.005 to 0.091 ppm, and copper from 0.22 to 0.85 ppm. The paper orders the mean concentrations as Pb > Cr > Ni > Cu > As.

Methods (brief)

The authors collected 25 unbranded whitening creams from three Karachi markets and stored them at room temperature before analysis. One gram of oven-dried cream was digested with concentrated nitric acid, filtered, diluted to 50 mL with deionized water, and analyzed for Pb, Ni, Cr, As, and Cu using Merck Super Nova60 kits. Each sample was measured in triplicate and reported as means with dispersion statistics.

Implications

Certification: Provides Pakistan-market occurrence data for lead, total chromium, nickel, total arsenic, and copper in unbranded whitening creams. Chromium is total Cr; the source does not speciate hexavalent chromium despite discussing its toxicology.

Courses: Useful for explaining how informal or unregulated cosmetic markets can create dermal exposure to heavy metals.

App: Supports the whitening-products page and consumer-product gap tracking for personal-care matrices.

Wiki pages this source may touch

Verification notes

  • The source measures unbranded whitening creams, not named consumer brands.
  • Arsenic and chromium are total element measurements; the source does not support inorganic arsenic or Cr(VI) routing.
  • Values are preserved in the source’s ppm unit. For these cream matrices, ppm is equivalent to mg/kg when treated as mass fraction.

Update history

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