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Heavy Metal Index

Platinum (Pt)

Platinum is relevant through industrial exposure, jewelry, catalysts, and platinum coordination complexes used as antitumor agents.

Overview

Platinum is relevant through industrial exposure, jewelry, catalysts, and platinum coordination complexes used as antitumor agents. Ufelle & Barchowsky 2021 attaches platinum to the wiki through hypersensitivity/platinosis, cisplatin-related nephrotoxicity, neurotoxicity, ototoxicity, marrow suppression, and carcinogenicity concerns.

Status

This page is a source-map stub created during the re-ingest of Ufelle & Barchowsky 2021. Substantive platinum-specific expansion awaits a dedicated ingest.

Frequently asked questions

Where does platinum exposure come from?

According to the page, platinum is relevant through industrial exposure, jewelry, catalysts, and platinum coordination complexes used as antitumor agents. The single source on the page, Ufelle & Barchowsky 2021, connects platinum to the wiki through these routes. The page does not provide food-specific occurrence or exposure data.

What health effects are associated with platinum?

The page cites Ufelle & Barchowsky 2021 for concerns including hypersensitivity/platinosis, cisplatin-related nephrotoxicity (kidney toxicity), neurotoxicity, ototoxicity (hearing effects), marrow suppression, and carcinogenicity. Several of these effects are tied specifically to platinum coordination complexes such as cisplatin, which are used as antitumor (chemotherapy) agents. The page does not quantify doses at which these effects occur.

Is there good coverage of platinum in food on this page?

No. The page is explicitly a source-map stub created during the re-ingest of Ufelle & Barchowsky 2021, and it states that substantive platinum-specific expansion awaits a dedicated ingest. It currently draws on a single source and provides no food-specific concentration or exposure figures.

What are the platinum compounds mentioned as relevant?

The page identifies platinum coordination complexes used as antitumor agents, naming cisplatin, carboplatin, and oxaliplatin in its species list. These are chemotherapy drugs, and the page connects cisplatin in particular to nephrotoxicity and related toxic effects. The page does not describe dietary sources of these compounds.

Sources

  • Ufelle & Barchowsky 2021 — Ufelle AC, Barchowsky A, 2021. Toxic Effects of Metals, Ch 23 in Casarett & Doull’s Essentials of Toxicology, 4th ed.

References

Works cited in this page’s text, in first-appearance order. See Sources for this page’s source inventory. Each title links to its source record, which carries the ingest receipt, the extracted values, and the file hash of the document it was built from.

  1. Toxic Effects of Metals (Chapter 23), in Casarett & Doull’s Essentials of Toxicology, Fourth EditionUfelle AC and Barchowsky A · Casarett & Doull’s Essentials of Toxicology, Fourth Edition. McGraw Hill Education · 2021 · www.mhprofessional.comTextbook

Update history

No substantive edit history is available in this build. The full commit record is available in git.