Overview
The EFSA AFC Panel established a tolerable weekly intake for aluminium of 1 mg Al/kg body weight per week in its May 2008 Scientific Opinion on the Safety of Aluminium from Dietary Intake, replacing the prior JECFA provisional tolerable weekly intake of 7 mg/kg b.w./week (a sevenfold reduction) (EFSA 2008). The TWI is anchored on neurotoxic, reproductive, and developmental effects in animal studies (EFSA 2008). The Panel concluded the TWI is likely to be exceeded in a significant part of the European population, particularly among consumers of foods containing aluminium-based food additives, infants on certain formulae, and adults consuming antacids (EFSA 2008).
JECFA subsequently aligned its PTWI to 1 mg/kg b.w./week (EFSA 2008).
| Parameter | Value |
|---|---|
| TWI | 1 mg Al/kg b.w./week |
| Prior JECFA PTWI (replaced) | 7 mg Al/kg b.w./week |
| Critical endpoints | Neurotoxicity, reproductive and developmental effects |
| Adopted | May 22, 2008 |
Sources
- EFSA 2008 — EFSA AFC Panel, 2008. Safety of Aluminium from Dietary Intake.
References
Works cited in this page’s text, in first-appearance order. This is not the full corpus for this page; it is only what the prose above draws on. The complete set of sources is listed under Sources below. Each title links to its source record, which carries the ingest receipt, the extracted values, and the file hash of the document it was built from.
- Safety of Aluminium from Dietary IntakeGovernment
Update history
The five most recent substantive edits to this page, classified major (evidence or structure moved), correction (a published value or statement was wrong and has been fixed), or minor (narrative rewritten without changing the underlying evidence). Each description is derived from what the edit did to this page; the linked commit is the authoritative record, routine regeneration passes are excluded, and the full version history lives in git. When DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.
| Commit | Date | Change | Description |
|---|---|---|---|
| a8052bb | 2026-08-09 | major | 1 source added; contamination-profile values revised; 4 sections added |