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Gao and Kannan 2020 - EDCs in U.S. feminine hygiene products

Gao and Kannan measured 24 endocrine-disrupting chemicals in 77 feminine hygiene products purchased in the Albany, New York area. The analyte panel was phthalates, parabens, bisphenols, and triclocarban; the study did not measure Pb, Cd, As, Hg, Ni, Al, Cr, Sn, Sb, U, or any other heavy-metal analyte. This page is therefore a product-occurrence context source only, useful for feminine-care exposure-method precedent and product-category routing, not for heavy-metal occurrence pools.

Key numbers

The product set comprised pads (n = 18), panty liners (n = 13), tampons (n = 12), wipes (n = 12), bactericidal creams and solutions (n = 14), deodorant sprays (n = 4), and powders (n = 4), purchased during February-March 2019 from supermarkets in and around Albany, New York. The products came from 47 popular brands, but this page reports category-level results only.

Table 1 reports phthalate concentrations as ng/g sample weight. Median and range for sum of nine phthalates (Σ9Phthalate) were:

Product categoryΣ9Phthalate medianΣ9Phthalate range
Pads, top layer (n = 18)362 ng/g205-11200 ng/g
Panty liners, top layer (n = 13)1830 ng/g168-34500 ng/g
Tampons (n = 12)1130 ng/g621-6160 ng/g
Wipes (n = 12)546 ng/g118-21700 ng/g
Bactericidal creams and solutions (n = 14)9.33 ng/g< LOD-47.9 ng/g
Deodorant sprays (n = 4)< LOD< LOD
Powders (n = 4)11.2 ng/g< LOD-26.7 ng/g

For the phthalate sub-panel, DMP, DEP, DBP, DIBP, and DEHP were detected in 100% of pads, panty liners, tampons, and wipes. Table 1 reports panty-liner medians of DMP 249 ng/g, DEP 386 ng/g, DIBP 299 ng/g, DBP 393 ng/g, and DEHP 164 ng/g. Tampons had the highest DEHP median among the absorbent products, 267 ng/g, with a DEHP range of 64.1-4680 ng/g.

Table 2 reports paraben concentrations as ng/g. Median and range for sum of six parabens (Σ6Paraben) were:

Product categoryΣ6Paraben medianΣ6Paraben range
Pads (n = 18)46.5 ng/g12.6-426 ng/g
Panty liners (n = 13)108 ng/g51.1-1700 ng/g
Tampons (n = 12)42.7 ng/g0.04-162 ng/g
Wipes (n = 12)149 ng/g0.41-15400 ng/g
Bactericidal creams and solutions (n = 14)5350 ng/g363-946000 ng/g
Deodorant sprays (n = 4)1060 ng/g233-14400 ng/g
Powders (n = 4)1167 ng/g179-2960 ng/g

The source highlights MeP, EtP, and PrP as the major parabens. In bactericidal creams and solutions, median MeP, EtP, and PrP were 2840, 743, and 278 ng/g, respectively; Table 2’s abstract summary gives EtP as 734 ng/g, while the table line gives 743, so the table value is used here and the source-side discrepancy is retained.

Table 3 reports bisphenols and triclocarban (TCC) as ng/g. Σ8Bisphenol was highest in panty liners, median 21.1 ng/g with range < LOD-160 ng/g; pads, tampons, and deodorant sprays had medians 5.59, 5.56, and 5.20 ng/g, respectively. TCC ranged from < LOD to 40.2 ng/g across all products; bactericidal creams/solutions and deodorant sprays had TCC detection frequencies of 46% and 50%.

Table 4 reports dermal absorption dose estimates as ng/kg-bw/day. Under the normal-skin absorption assumptions, median total phthalate doses were 0.250 for pads, 0.844 for panty liners, and 1.309 ng/kg-bw/day for tampons; median total paraben doses were 0.322, 0.499, and 0.493 ng/kg-bw/day; median total bisphenol doses were 0.039, 0.097, and 0.064 ng/kg-bw/day. The text states that under a 100% absorption scenario, feminine hygiene products contributed 27.9% of total phthalate exposure, with tampons, panty liners, and pads accounting for 15.2%, 9.8%, and 2.9% of total phthalate exposure, respectively.

Methods (brief)

Samples were analyzed within one week of collection. For pads and panty liners, only the skin-contacting surface layer was analyzed; for other products, the entire product was analyzed. Phthalates were measured by Agilent 7890A GC coupled to Agilent 5975C MS. Parabens, bisphenols, and TCC were measured by Shimadzu HPLC coupled to API 3200 ESI-MS/MS. QA/QC included two method blanks and two matrix-spike samples per batch of 20 samples, internal-standard recovery correction, procedural-blank subtraction, phthalate LOQs of 2-10 ng/g, and paraben/bisphenol/TCC LOQs of 0.1-0.4 ng/g. The paper does not report any elemental method, digestion, ICP-MS, ICP-OES, AAS, or heavy-metal analysis.

Implications

Certification: This source contributes no heavy-metal occurrence values and should not move any HMTc metals threshold. Its relevance is product-family context for feminine-care matrices, especially how absorbent-layer selection, top-layer sampling, and dermal-exposure modelling were handled in a peer-reviewed U.S. product-occurrence study.

Courses: The paper is a useful teaching example for separating routeable product occurrence from routeable metals occurrence. It also illustrates how product-form subgroups, skin-contact layer selection, LOQ handling, and dermal absorption assumptions shape exposure estimates.

App: The source can support non-metal context cards for feminine-care products, but the consumer app should not present it as evidence of heavy-metal contamination.

Microbiome: The paper mentions bacterial vaginosis only as a possible EDC-related research area in the conclusion; it does not measure microbiome endpoints.

Wiki pages this source may touch

Verification notes

Identity checks before drafting found no existing wiki/sources/ hit for DOI 10.1016/j.envint.2020.105465, raw handle MFK_paper-19-gao-2020-edcs-feminine-products, cite key gao2020-feminine-hygiene-edcs, or the exact title. The DOI, title, byline, journal, year, and CC BY-NC-ND license were checked against the first page. Tables 1-4 and Sections 2.2-2.4 and 3.1-3.6 were re-opened from /tmp/hmi-fem-011.txt; all concentrations above preserve the source’s ng/g and ng/kg-bw/day units without conversion. metals: [] is intentional: the paper measures no heavy metals, no total arsenic, no inorganic arsenic, no mercury species, no chromium species, and no organotin/tin. The source states that products came from 47 popular brands, but this page reports only category-level values under the brand firewall. Product slugs were checked against the closed taxonomy; menstrual-pads covers both pads and panty liners because no narrower panty-liner slug exists, and intimate-washes-cleansers covers the bactericidal creams/solutions category because no narrower closed slug exists. npm run evidence:source-routes exited 0 and generated six product routes; routing_malformed.csv contains an advisory-only warning for intentionally empty ingredients and metals.

Page history

The five most recent substantive edits to this page. The full version history lives in git; when DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.

CommitDateDescription
4039d202026-06-10scope: broaden ingest to the full upstream+downstream literature (marine, atmospheric, attribution, exposure, toxicology) — inclusion is the default