Skip to content
Heavy Metal Index

Determination of Nickel Concentration in the Breast Milk of Lactating Mothers Living In Hilla City

Source

Abaas and colleagues measured nickel in breast milk from lactating mothers living in Hilla City, Iraq.

Page snapshot
Cited by4 pages
Metals measured1
Evidence tierA
Year2018

Overview

Abaas and colleagues measured nickel in breast milk from lactating mothers living in Hilla City, Iraq. The study is routeable for human-milk nickel exposure because it reports breast-milk nickel concentrations in ppb and evaluates associations with maternal and environmental variables. It is human-milk exposure evidence, not infant formula evidence.

Key numbers

  • Sample size: 68 apparently healthy lactating mothers, sampled mid-February through end of April 2012.
  • Mean nickel concentration in breast milk: 23.83 +/- 15.57 ppb (µg/L).
  • Subgroup means (mean ± SD, µg/L): rural (n=36) 30.81 ± 16.59 vs urban (n=32) 24.95 ± 19.55 (p<0.05); near street (n=32) 31.59 ± 17.41 vs far from street (n=36) 25.3 ± 18.89; near industrial area (n=22) 30.99 ± 12.98 vs normal area (n=46) 24.31 ± 13.40; tap water (n=43) 26.15 ± 2.31 vs bottled (n=18) 17.4 ± 2.43 vs river (n=7) 22.12 ± 5.42; smoker (n=8) 47.5 ± 20.05 vs non-smoker (n=60) 20.68 ± 11.89.
  • The authors describe the overall mean as high compared with concentrations reported in Turkey (3 µg/L) and the USA (15 µg/L) per the paper’s Table 8.
  • Prevalence of mothers with abnormal nickel concentration: 45 of 68 (66%) per Table 9. The abstract’s “99% and 93% respectively” appears to be templating leftover from a multi-metal study; the paper itself only reports nickel and Table 9 is the only prevalence table.

Methods (brief)

Ten millilitres of breast milk were self-expressed by manual breast pump after washing the breast with deionized water and discarding the first drops; midstream milk was collected into sterile polypropylene tubes, transported at -18 to -21 °C, and stored at -30 °C at the chemical laboratory of the College of Science, Babylon University. Nickel was determined by graphite furnace atomic absorption spectrometry with a calibration curve at 232 nm (Figure 1). Statistical analysis used SPSS v17 with Student’s t-test and one-way ANOVA at p<0.05 significance. The paper reports total nickel concentration.

Implications

Certification: Human-milk exposure context only; not a commercial product benchmark source.

Courses: Useful for geographic-variance teaching in infant exposure.

App: Can inform human-milk exposure context if the app tracks breastfeeding separately.

Wiki pages this source may touch

Verification notes

The filename came from a human-milk Ni gap and matches the source content. No speciation issue applies for nickel.

Cite-key/filename caveat for Karen: the assigned cite-key abaas2018-breast-milk-nickel was derived from a misreading of the byline. The PDF’s first-author surname is Nassir (Ishtar Munim Nassir, Babylon Health Directorate); “Abaas” is the second author’s first name (Abaas Noor Al-Sharify). A future rename to nassir2018-breast-milk-nickel would be more accurate. The authors frontmatter has been corrected; the cite-key itself is preserved here under the hard-constraint rule that the audit step does not rename cite-keys or raw handles.

The paper’s abstract contains two internal inconsistencies that do not affect the wiki extraction but are flagged here for transparency: (1) the abstract says higher Ni concentrations were associated with “living in urban regions”, but Table 1 and the Discussion both state Ni was higher in rural mothers — Table 1’s data is treated as authoritative; (2) Table 8 labels the comparison column “Cd(µg/L)” while the entire paper measures Ni — the values in Table 8 are Ni, not Cd, as confirmed by the matching 23.83 ± 15.57 figure.

Update history

This page has no substantive edit history yet. Future revisions will be recorded here once the change lands in git.