Overview
The August 2005 ATSDR ToxFAQs fact sheet (Tox fact sheet #55) is the two-page consumer-facing summary of the ATSDR 2005 Toxicological Profile for Tin and Compounds (Update). It carries no primary data of its own; its function in the wiki corpus is to document the US federal occupational and food-additive regulatory framework for tin and tin compounds as the agency communicated it to non-specialist audiences in 2005, and to capture the public-health framing ATSDR used to distinguish inorganic tin from the substantially more toxic organotin compounds. The full quantitative profile lives in the sibling page Toxicological Profile for Tin and Tin Compounds.
Key numbers
- OSHA workplace air limits. Organotin compounds — 0.1 mg/m³. Inorganic tin compounds, except oxides — 2.0 mg/m³. (The fact sheet does not attach an averaging period to either PEL; OSHA’s underlying PELs are eight-hour time-weighted averages, but the fact sheet does not say so.) The twenty-fold occupational limit gap is the regulatory expression of the same inorganic-vs-organotin toxicity differential that the full toxicological profile expresses through the MRL ladder.
- FDA food-contact and food-additive regulation. FDA regulates the use of some organic tin compounds in coatings and plastic food packaging. FDA has also set limits for the use of an inorganic tin compound, stannous chloride, as a food additive. The fact sheet does not state numeric values for either; they live in the underlying FDA regulations cited by the full toxicological profile.
- NPL site occurrence (1,662 total NPL sites at time of writing). Metallic tin and inorganic tin compounds — identified at at least 214 sites. Organic tin compounds — identified at at least 8 sites.
- Tin-lined can lacquering prevalence. Greater than 90 percent of tin-lined cans used for food are protected with lacquer (the lacquer prevents the elemental-tin-to-canned-food dissolution reaction).
- Cancer classification status (as of 2005). DHHS, IARC, and EPA have not classified metallic tin or inorganic tin compounds for carcinogenicity. EPA has determined that tributyltin oxide is not classifiable as to human carcinogenicity. Triphenyltin hydroxide produced cancer in rats and mice after long-term oral administration in published animal studies.
Methods (brief)
ATSDR ToxFAQs fact sheet; no analytical methods. Two-page consumer-facing summary distilled from the parallel ATSDR 2005 Toxicological Profile for Tin and Compounds (Update), which is cited as the sole reference. Health-effects framing follows the standard ATSDR ToxFAQs structure: what the substance is, environmental fate, exposure routes, health effects (general adult), cancer, children, exposure-reduction guidance, biomonitoring, and federal regulation. No original data; no derived MRLs (the MRLs live in the full profile); no exposure modeling.
Evidence fitness
This source supports context only. It restates qualitative conclusions and a small set of regulatory values from the underlying ATSDR 2005 toxicological profile and from OSHA / FDA standards in force at time of writing. It carries no occurrence measurements, no LODs, no sampling strata, and no statistical summaries. Cite this page when a wiki claim needs the US-federal consumer-health framing for tin (the inorganic-vs-organotin split as ATSDR communicated it to the public, the OSHA workplace limits, the FDA food-contact framework, the >90 percent lacquer prevalence in tin-lined food cans). Do not cite this page as primary evidence for any tin concentration in any food matrix; route those claims to the sibling toxicological profile or to primary occurrence studies.
Implications
- Certification: Captures the US-federal occupational and food-additive regulatory frame for tin (OSHA 0.1 mg/m³ organotins; OSHA 2.0 mg/m³ inorganic tin except oxides; FDA stannous-chloride food-additive limits; FDA organic-tin food-contact-coating regulation) in the form the agency communicated to non-specialist audiences. The factual content overlaps entirely with the full toxicological profile sibling page; this page exists in the corpus so that future regulatory-affairs queries that name “ATSDR ToxFAQs” or “tfacts55” can land on the document by name rather than being redirected to the longer profile.
- Courses: Useful as a one-page consumer-health-communications artifact in any educator-facing module on how federal agencies translate the species-stratified MRL framework (inorganic tin at intermediate-duration oral MRL 0.3 mg/kg/day; tributyltin oxide at intermediate and chronic oral MRL 0.0003 mg/kg/day per the full profile) into a public-facing risk message.
- App: No
contamination_profilecontribution. The page is qualitative federal communication, not occurrence data.
Provenance notes
Source PDF is the ATSDR ToxFAQs fact sheet for tin (filename tfacts55 2.pdf indicates the second copy of fact sheet #55 in the Manual Fetch source-retrieval June 3 batch). The fact sheet is a US government work and is in the public domain. The canonical URL points to ATSDR’s hosted PDF at atsdr.cdc.gov; the document is referenced as “TIN AND TIN COMPOUNDS — Division of Toxicology ToxFAQs — August 2005” in its own header. The single reference cited by the fact sheet is the ATSDR 2005 Toxicological Profile for Tin and Compounds (Update), which is the sibling source page Toxicological Profile for Tin and Tin Compounds. No DOI is assigned.
Related evidence
Update history
No substantive edit history is available in this build. The full commit record is available in git.