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Chagonda et al. 2023 - Harare child blood lead

Chagonda and colleagues measured blood lead levels in 86 children under six years old living in Mbare, a high-density Harare suburb with old housing, possible lead-based paint, aged water infrastructure, and nearby industrial activity. The study also measured lead in soil, tap and borehole drinking water, paint chips, and puddle water; it is exposure and environmental-source evidence, not cookware occurrence evidence.

Key numbers

The overall mean blood lead level was 4.3 +/- 0.75 ug/dL in Table 1, with 12 of 86 children (13.95%, reported as 14.0% in the table) above 5.0 ug/dL. Mean blood lead was 4.3 +/- 0.78 ug/dL in males and 4.4 +/- 0.71 ug/dL in females, with no significant gender difference.

Table 4 reports lead levels in 10 specimens per environmental matrix:

Environmental specimenPb mean +/- SDRangeComparator listed by source
Soil89.8 +/- 71.1 mg/kg3.34-177.5 mg/kg250-400 mg/kg
Drinking water, community boreholes1.1 +/- 0.7 ug/L0.3-2.0 ug/LUp to 10 ug/L
Drinking water, community tap1.9 +/- 0.9 ug/L0.7-3.3 ug/LUp to 10 ug/L
Paint chips82.0 +/- 57.4 mg/kg9.64-169.2 mg/kgUp to 600 mg/kg
Water from puddles1.1 +/- 0.5 ug/L0.6-1.8 ug/LNot listed in extracted table continuation

In multivariate logistic regression, history of unexplained abdominal pain was associated with blood lead above 5 ug/dL after adjustment for petrol exposure and toy preference (OR 4.39, 95% CI 1.07-17.9). Children who played with random objects had higher blood lead than children who played with plastic toys in an unshown comparison cited in the results section (4.6 +/- 0.79 versus 4.2 +/- 0.70 ug/dL; p = 0.04).

Methods (brief)

The study used a cross-sectional design and enrolled children aged six years and below who had lived in the study site from birth. Whole blood was collected into EDTA tubes, diluted with 5% nitric acid, centrifuged, and analyzed for lead by flame atomic absorption spectrophotometry at 283.3 nm using a Varian AA-1275 instrument; the analytical sensitivity was 1 ug/dL.

Environmental sampling included 10 g paint-chip scrapings from participating apartments, 20 g soil samples from play areas, and 100 mL water samples from puddles, communal boreholes, and municipal taps. Water samples were digested with hot concentrated nitric acid; soil and paint chips were extracted with aqua regia before flame AAS analysis. The environmental values are lead-only total/bioaccessible measurements and do not provide other HMTc analytes.

Implications

Certification: Do not route this source into cookware or product-occurrence benchmark pools. The auto-fetch filename points at cookware, but the paper measured child blood, residential environmental media, and questionnaire risk factors rather than metals leaching from cookware.

Courses: Useful as an exposure-routing example for older housing, paint chips, soil/dust, and water-infrastructure pathways in a consumer-safety heavy-metals curriculum.

App: Context-only for exposure education and risk-factor language; it does not provide ingredient or product concentration distributions.

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Verification notes

This page was built from the PDF text, including the abstract, methods, Tables 1 and 4, results, and discussion. The abstract appears to omit the micro symbol in “4.3 +/- 0.75 ug/dL” in text extraction; the tables and surrounding prose use ug/dL for blood lead. Products and ingredients are intentionally empty because the paper does not measure a consumer-product concentration matrix. The source reports total lead only.

Page history

The five most recent substantive edits to this page. The full version history lives in git; when DOI minting comes online (see schema docs), each entry below will also link to a version-pinned DataCite DOI.

CommitDateDescription
4039d202026-06-10scope: broaden ingest to the full upstream+downstream literature (marine, atmospheric, attribution, exposure, toxicology) — inclusion is the default