{
  "schema_version": "2.0.0",
  "source_index_schema_version": "2.0.0",
  "manifest_kind": "heavy_metal_index_evidence_packet",
  "retrieval_timestamp": "2026-09-26T10:46:29.992Z",
  "page": {
    "slug": "sources/crosera2015-tio2-nanoparticle-skin-penetration-hacat",
    "title": "Titanium Dioxide Nanoparticle Penetration into the Skin and Effects on HaCaT Cells",
    "description": null,
    "page_type": "source",
    "audience": [
      "regulator",
      "researcher"
    ],
    "canonical_url": "https://heavymetalindex.com/sources/crosera2015-tio2-nanoparticle-skin-penetration-hacat",
    "wiki_doi": null
  },
  "content_pin": {
    "status": "unpinned",
    "reason": "Git history and a matching verified prior manifest are unavailable.",
    "content_hash_scheme": "sha256-utf8-authored-markdown-v2",
    "content_hash_description": "Strip leading YAML; remove only generated hmi-page-history and hmi-page-references marker blocks; trim trailing whitespace and append one LF. Other Markdown bytes are preserved.",
    "content_sha256": "04581788fb923865152c91df72c642265792b6010b1e6783138c0fff21da2f0a",
    "content_bytes": 1859,
    "metadata_sha256": "91aea34dbcc88422ff146d33cb77919ea79a054d9c59040fe8248fd6111b9814",
    "metadata_hash_description": "SHA-256 of recursively key-sorted JSON from parsed YAML, excluding updated and numeric sources (generated display metadata). All other frontmatter fields are included.",
    "published_body_sha256": "967eefc6c8c1f9f630d0fcabdf145cc3912429cf0213157d45352bf4d94a2726",
    "published_body_bytes": 2097,
    "published_checksum_note": "Published-body and full-Markdown checksums describe the build input, including generated display sections. They are not claimed to equal the Git revision's display sections.",
    "markdown_sha256": "a90f8ae5d4c06ca11cbed278bdbaa98ecfe29ed7c9261c42ea70ca08af8d4f98",
    "markdown_bytes": 4101,
    "git_commit_sha": null,
    "last_commit_sha": null,
    "last_commit_date": null,
    "git_remote": "https://github.com/paleofoundation/heavymetalindex",
    "verify_command": null
  },
  "contributing_sources": [
    "sources/danishepa2015-dermal-absorption-nano-tio2-zno-sunscreen",
    "sources/sccs2014-titanium-dioxide-nano-opinion-1516-13"
  ],
  "data_downloads": [],
  "ingest_contract": {
    "metadata_complete": false,
    "ingest_complete": false,
    "gaps": [
      "routing_input:products left empty: titanium dioxide nanoparticles were applied in synthetic sweat, not in a sunscreen or other product row; the study is dermal-penetration context for mineral sunscreens"
    ],
    "completion_note": "Metadata completeness alone does not prove extraction, routing, or primary-source coverage. Completed ingest requires its reconciliation and route audits."
  },
  "license": {
    "prose": "CC BY 4.0",
    "structured_data": "EU database rights reserved — see https://heavymetalindex.com/licensing",
    "attribution": "Heavy Metal Index (heavymetalindex.com), Institute of Contaminant Standards. Cite canonical_url or wiki_doi.",
    "contact": "karen@paleofoundation.com"
  },
  "attestation": {
    "for_use": "Citation, regulatory submission, or peer-review supplementary record.",
    "verifiable_by": "This manifest reports build-input checksums but has no verified Git pin. It cannot establish that these page bytes correspond to a named Git revision.",
    "not_a_certification": "This manifest records publication provenance. It does not certify products or independently validate the page's scientific claims.",
    "license_terms": "https://heavymetalindex.com/licensing"
  },
  "generated_at": "2026-09-26T08:32:01.834Z"
}